Current perspectives on neuromodulation in ALS patients: A systematic review and meta-analysis

AM Jiménez-García, G Bonnel, A Álvarez-Mota, N Arias - Plos one, 2024 - journals.plos.org
Amyotrophic Lateral Sclerosis (ALS) is a progressive neurodegenerative disease that affects
motor neurons, resulting in muscle weakness, paralysis, and eventually patient mortality. In …

Brain stimulation as a therapeutic tool in amyotrophic lateral sclerosis: Current status and interaction with mechanisms of altered cortical excitability

F Ranieri, S Mariotto, R Dubbioso… - Frontiers in …, 2021 - frontiersin.org
In the last 20 years, several modalities of neuromodulation, mainly based on non-invasive
brain stimulation (NIBS) techniques, have been tested as a non-pharmacological …

[HTML][HTML] The landscape of neurophysiological outcome measures in ALS interventional trials: a systematic review

N Ahmed, MR Baker, J Bashford - Clinical Neurophysiology, 2022 - Elsevier
Objective We collated all interventional clinical trials in amyotrophic lateral sclerosis (ALS),
which utilised at least one neurophysiological technique as a primary or secondary outcome …

Efficacy of non-pharmacological interventions for individuals with amyotrophic lateral sclerosis: systematic review and network meta-analysis of randomized control …

Z Li, H Kang - Scientific Reports, 2024 - nature.com
This network meta-analysis (NMA) aimed to compare the efficacy of five non-
pharmacological interventions, including exercise intervention (EI), nutritional intervention …

Current potential therapeutics of amyotrophic lateral sclerosis

L Lu, Y Deng, R Xu - Frontiers in Neurology, 2024 - frontiersin.org
Amyotrophic lateral sclerosis (ALS) is a debilitating motor neurological disorder for which
there is still no cure. The disease seriously jeopardizes the health and lifespan of adult …

[HTML][HTML] Exploring Advancements in the Treatment of Amyotrophic Lateral Sclerosis: A Comprehensive Review of Current Modalities and Future Prospects

P Hoxhaj, N Hastings, MP Kachhadia, R Gupta… - Cureus, 2023 - ncbi.nlm.nih.gov
Amyotrophic lateral sclerosis (ALS) is a fatal and incurable disease requiring a
multidisciplinary treatment approach and a collaborative therapeutic effort. A combination of …

Physical therapy for the management of motor symptoms in amyotrophic lateral sclerosis: protocol for a systematic review

ST Silva, AA de Souza, K Pondofe, LP de Melo… - BMJ open, 2022 - bmjopen.bmj.com
Introduction The prescription of an intervention plan can be challenging for the physical
therapist, considering clinical phenotypes, individual prognosis and the rapid, progressive …

A perspective on therapies for amyotrophic lateral sclerosis: can disease progression be curbed?

X Xu, D Shen, Y Gao, Q Zhou, Y Ni, H Meng… - Translational …, 2021 - Springer
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease involving
both upper and lower motor neurons, leading to paralysis and eventually death …

Neuromuscular magnetic stimulation counteracts muscle decline in ALS patients: Results of a randomized, double-blind, controlled study

A Musarò, G Dobrowolny, C Cambieri, E Onesti… - Scientific Reports, 2019 - nature.com
The aim of the study was to verify whether neuromuscular magnetic stimulation (NMMS)
improves muscle function in spinal-onset amyotrophic lateral sclerosis (ALS) patients …

Novel approaches to motoneuron disease/ALS treatment using non-invasive brain and spinal stimulation: IFCN handbook chapter

V Di Lazzaro, F Ranieri, M Bączyk, M de Carvalho… - Clinical …, 2023 - Elsevier
Non-invasive brain stimulation techniques have been exploited in motor neuron disease
(MND) with multifold objectives: to support the diagnosis, to get insights in the …