Sleep deprivation accelerates the progression of Alzheimer's disease by influencing Aβ-related metabolism
L Chen, J Huang, L Yang, XA Zeng, Y Zhang… - Neuroscience …, 2017 - Elsevier
Sleep disorders have previously been connected with the neurodegenerative pathology of
Alzheimer's disease (AD) due to the aggregation of β-amyloid (Aβ) peptides and tau …
Alzheimer's disease (AD) due to the aggregation of β-amyloid (Aβ) peptides and tau …
Chronic sleep restriction induces Aβ accumulation by disrupting the balance of Aβ production and clearance in rats
B Zhao, P Liu, M Wei, Y Li, J Liu, L Ma, S Shang… - Neurochemical …, 2019 - Springer
Amyloid-β (Aβ) plays an important role in Alzheimer's disease (AD) pathogenesis, and
growing evidence has shown that poor sleep quality is one of the risk factors for AD, but the …
growing evidence has shown that poor sleep quality is one of the risk factors for AD, but the …
Activation of inflammation is associated with amyloid-β accumulation induced by chronic sleep restriction in rats
P Liu, B Zhao, M Wei, Y Li, J Liu, L Ma… - Journal of …, 2020 - content.iospress.com
Alzheimer's disease (AD) is the most common age-associated neurodegenerative disease
featured by progressive learning and memory deficit, and Aβ was identified as playing a key …
featured by progressive learning and memory deficit, and Aβ was identified as playing a key …
Sleep deprivation impairs memory, tau metabolism, and synaptic integrity of a mouse model of Alzheimer's disease with plaques and tangles
A Di Meco, YB Joshi, D Praticò - Neurobiology of aging, 2014 - Elsevier
Several studies have highlighted the frequency of sleep disturbances in Alzheimer's disease
(AD). However, whether they are secondary to the disease or per se increase its risk …
(AD). However, whether they are secondary to the disease or per se increase its risk …
Chronic sleep deprivation exacerbates cognitive and synaptic plasticity impairments in APP/PS1 transgenic mice
C Wang, WR Gao, J Yin, ZJ Wang, JS Qi, HY Cai… - Behavioural Brain …, 2021 - Elsevier
Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by
cognitive deficits. Sleep deprivation (SD) could lead to memory deficits, and it was a …
cognitive deficits. Sleep deprivation (SD) could lead to memory deficits, and it was a …
Reduced slow-wave activity and autonomic dysfunction during sleep precede cognitive deficits in Alzheimer's disease transgenic mice
CW Chen, YT Kwok, YT Cheng, YS Huang, TBJ Kuo… - Scientific reports, 2023 - nature.com
Occurrence of amyloid-β (Aβ) aggregation in brain begins before the clinical onset of
Alzheimer's disease (AD), as preclinical AD. Studies have reported that sleep problems and …
Alzheimer's disease (AD), as preclinical AD. Studies have reported that sleep problems and …
Chronic Sleep Restriction Induces Cognitive Deficits and Cortical Beta‐Amyloid Deposition in Mice via BACE 1‐Antisense Activation
HY Zhao, HJ Wu, JL He, JH Zhuang… - CNS neuroscience & …, 2017 - Wiley Online Library
Aims To clarify the correlation between chronic sleep restriction (CSR) and sporadic
Alzheimer disease (AD), we determined in wild‐type mice the impact of CSR, on cognitive …
Alzheimer disease (AD), we determined in wild‐type mice the impact of CSR, on cognitive …
Chronic sleep fragmentation exacerbates amyloid β deposition in Alzheimer's disease model mice
Sleep fragmentation due to intermittent nocturnal arousal resulting in a reduction of total
sleep time and sleep efficiency is a common symptom among people with Alzheimer's …
sleep time and sleep efficiency is a common symptom among people with Alzheimer's …
Sleep deficiency promotes Alzheimer's disease development and progression
YN Lv, Y Cui, B Zhang, SM Huang - Frontiers in neurology, 2022 - frontiersin.org
Sleep disorders are a common health problem in modern society. Long-term sleep
deficiency increases the risk for Alzheimer's disease. However, the exact mechanisms by …
deficiency increases the risk for Alzheimer's disease. However, the exact mechanisms by …
[HTML][HTML] Sleep alleviates AD-related neuropathological processes
H Malkki - Nature reviews Neurology, 2013 - nature.com
Sleep disturbances have previously been associated with Alzheimer disease (AD) and age-
related cognitive decline. Now, three studies have addressed the link between sleep and …
related cognitive decline. Now, three studies have addressed the link between sleep and …
相关搜索
- alzheimer's disease sleep deprivation
- tau metabolism sleep deprivation
- amyloid β sleep restriction
- alzheimer's disease tau metabolism
- clearance in rats sleep restriction
- plasticity impairments sleep deprivation
- synaptic integrity sleep deprivation
- plaques and tangles sleep deprivation
- transgenic mice sleep deprivation