An increased expression and cytoplasmic abundance of the ubiquitous RNA binding protein
human antigen R (HuR) is critically implicated in the dysregulated control of post …

Increased abundance of the mRNA-binding protein human antigen R (HuR) is a
characteristic feature of many cancers and frequently associated with a high grade …

HuR plays an important role in tumor cell survival mainly through posttranscriptional
upregulation of prominent anti-apoptotic genes. In addition, HuR can inhibit the translation of …

The RNA-binding protein HuR can stabilize and/or regulate the translation of target mRNAs,
thereby affecting the cellular responses to immune, proliferative, and damaging agents …

Caspase-2 represents the most conserved member of the caspase family, which exhibits
features of both initiator and effector caspases. Using ribonucleoprotein (RNP) …

In response to damaging agents, cells alter gene expression patterns through transcriptional
and post-transcriptional mechanisms. Among the major post-transcriptional regulators of …

Background HuR, an RNA binding protein involved in the post-transcriptional regulation of a
wide spectrum of mRNAs, has been demonstrated to be a determinant of carcinogenesis …

The RNA-binding protein human antigen R (HuR) is a well-established regulator of gene
expression at the posttranscriptional level. Its dysregulation has been implicated in various …

The RNA-binding proteins (RBPs) are critical trans factors that associate with specific cis
elements present in mRNAs whose stability and translation are subject to regulation. The …

A well-studied RNA-binding protein Hu Antigen-R (HuR), controls post-transcriptional gene
regulation and undergoes stress-activated caspase-3 dependent cleavage in cancer cells …