[HTML][HTML] Role of hydrogen sulfide donors in cancer development and progression

EE Ngowi, A Afzal, M Sarfraz, S Khattak… - … Journal of Biological …, 2021 - ncbi.nlm.nih.gov
In recent years, a vast number of potential cancer therapeutic targets have emerged.
However, developing efficient and effective drugs for the targets is of major concern …

Hydrogen sulfide and its donors: Novel antitumor and antimetastatic agents for liver cancer

CH Zhang, ZL Jiang, Y Meng, WY Yang, XY Zhang… - Cellular …, 2023 - Elsevier
Hepatocellular carcinoma (HCC) is the sixth most frequent human cancer and the world's
third most significant cause of cancer mortality. HCC treatment has recently improved, but its …

Hydrogen sulfide in cancer: friend or foe?

D Wu, W Si, M Wang, S Lv, A Ji, Y Li - Nitric oxide, 2015 - Elsevier
Hydrogen sulfide (H 2 S) is the third gaseous signaling molecule that plays important roles
in cancer biological processes. Recent studies indicate that H 2 S has both pro-cancer and …

Hydrogen sulfide biology and its role in cancer

S Khattak, MA Rauf, NH Khan, QQ Zhang, HJ Chen… - Molecules, 2022 - mdpi.com
Hydrogen sulfide (H2S) is an endogenous biologically active gas produced in mammalian
tissues. It plays a very critical role in many pathophysiological processes in the body. It can …

Hydrogen sulfide and cancer

MR Hellmich, C Szabo - Chemistry, Biochemistry and Pharmacology of …, 2015 - Springer
Recent studies revealed increased expression of various hydrogen sulfide (H 2 S)-
producing enzymes in cancer cells of various tissue types, and new roles of H 2 S in the …

A review of hydrogen sulfide synthesis, metabolism, and measurement: is modulation of hydrogen sulfide a novel therapeutic for cancer?

X Cao, L Ding, Z Xie, Y Yang, M Whiteman… - Antioxidants & redox …, 2019 - liebertpub.com
Abstract Significance: Hydrogen sulfide (H2S) has been recognized as the third gaseous
transmitter alongside nitric oxide and carbon monoxide. In the past decade, numerous …

Recent advances in the role of endogenous hydrogen sulphide in cancer cells

HJ Chen, K Li, YZ Qin, JJ Zhou, T Li, L Qian… - Cell …, 2023 - Wiley Online Library
Hydrogen sulphide (H2S) is a gaseous neurotransmitter that can be self‐synthesized by
living organisms. With the deepening of research, the pathophysiological mechanisms of …

Molecular functions of hydrogen sulfide in cancer

RE Shackelford, IZ Mohammad, AT Meram, D Kim… - Pathophysiology, 2021 - mdpi.com
Hydrogen sulfide (H2S) is a gasotransmitter that exerts a multitude of functions in both
physiologic and pathophysiologic processes. H2S-synthesizing enzymes are increased in a …

The hidden role of hydrogen sulfide metabolism in cancer

RH Wang, YH Chu, KT Lin - International Journal of Molecular Sciences, 2021 - mdpi.com
Hydrogen Sulfide (H2S), an endogenously produced gasotransmitter, is involved in various
important physiological and disease conditions, including vasodilation, stimulation of …

Hydrogen sulfide metabolism and signaling in the tumor microenvironment

A Giuffrè, CS Tomé, DGF Fernandes, K Zuhra… - … : The Main Driver of …, 2020 - Springer
Abstract Hydrogen sulfide (H 2 S), while historically perceived merely as a toxicant, has
progressively emerged as a key regulator of numerous processes in mammalian physiology …