HIV-associated neurotoxicity and cognitive decline: Therapeutic implications
DR Wallace - Pharmacology & Therapeutics, 2022 - Elsevier
As our understanding of changes to the neurological system has improved, it has become
clear that patients who have contracted human immunodeficiency virus type 1 (HIV-1) can …
clear that patients who have contracted human immunodeficiency virus type 1 (HIV-1) can …
HIV neurotoxicity: potential therapeutic interventions
DR Wallace - BioMed Research International, 2006 - Wiley Online Library
Individuals suffering from human immunodeficiency virus type 1 (HIV‐1) infection suffer from
a wide range of neurological deficits. The most pronounced are the motor and cognitive …
a wide range of neurological deficits. The most pronounced are the motor and cognitive …
Could antiretroviral neurotoxicity play a role in the pathogenesis of cognitive impairment in treated HIV disease?
J Underwood, KR Robertson, A Winston - Aids, 2015 - journals.lww.com
Whilst effective antiretroviral therapy is protective against the more severe forms of HIV-
associated brain disease, there remains a large burden of clinically symptomatic cognitive …
associated brain disease, there remains a large burden of clinically symptomatic cognitive …
HIV-associated neurocognitive disorder: pathogenesis and therapeutic opportunities
KA Lindl, DR Marks, DL Kolson… - Journal of neuroimmune …, 2010 - Springer
Human immunodeficiency virus type 1 (HIV) infection presently affects more that 40 million
people worldwide, and is associated with central nervous system (CNS) disruption in at least …
people worldwide, and is associated with central nervous system (CNS) disruption in at least …
Developing neuroprotective strategies for treatment of HIV-associated neurocognitive dysfunction
JA Rumbaugh, J Steiner, N Sacktor, A Nath - Future HIV therapy, 2008 - Taylor & Francis
Important advances have been made in recent years in identifying the molecular
mechanisms of HIV neuropathogenesis. Defining the pathways leading to HIV dementia has …
mechanisms of HIV neuropathogenesis. Defining the pathways leading to HIV dementia has …
HIV-associated neurocognitive disorders and antiretroviral therapy: current concepts and controversies
MR Etherton, JL Lyons, KL Ard - Current infectious disease reports, 2015 - Springer
Antiretroviral drugs may help prevent neurological decline in individuals with HIV infection
by suppressing viral replication and associated chronic immune activation in the central …
by suppressing viral replication and associated chronic immune activation in the central …
Mechanisms underlying HIV-associated cognitive impairment and emerging therapies for its management
People living with HIV are affected by the chronic consequences of neurocognitive
impairment (NCI) despite antiretroviral therapies that suppress viral replication, improve …
impairment (NCI) despite antiretroviral therapies that suppress viral replication, improve …
Treatment of HIV in the CNS: effects of antiretroviral therapy and the promise of non-antiretroviral therapeutics
The growing recognition of the burden of neurologic disease associated with HIV infection in
the last decade has led to renewed efforts to characterize the pathophysiology of the virus …
the last decade has led to renewed efforts to characterize the pathophysiology of the virus …
CNS neurotoxicity of antiretrovirals
The development of novel antiretroviral treatments has led to a significant turning point in the
fight against HIV. Although therapy leads to virologic suppression and prolonged life …
fight against HIV. Although therapy leads to virologic suppression and prolonged life …
Neurobiology of HIV
B Hult, G Chana, E Masliah, I Everall - International Review of …, 2008 - Taylor & Francis
The importance of HIV cognitive impairment, including HIV associated dementia (HAD) and
minor cognitive/motor disorder, has continued in the era of highly active antiretroviral …
minor cognitive/motor disorder, has continued in the era of highly active antiretroviral …