Vaccines are cost-effective for the prevention of infectious diseases and have significantly
reduced mortality and morbidity. Novel approaches are needed to develop safe and …

Nasal drug delivery is advantageous when compared with other routes of drug delivery as it
avoids the hepatic first-pass effect, blood–brain barrier penetration, and compliance issues …

Mucosal surfaces are the major entrance for infectious pathogens and therefore mucosal
immune responses serve as a first line of defence. Most current immunization procedures …

Sixty‐five healthy adult volunteers were immunized four times at 1‐week intervals with an
inactivated whole‐virus influenza vaccine based on the strain A/New Caledonia/20/99 …

New cationic nanoparticles (SMBV™) were evaluated for use as a nasal vaccine delivery
system for two recombinant proteins: HBsAg and β-galactosidase. Each protein was …

Vaccine delivery via mucosal surfaces is an interesting alternative to parenteral vaccine
administration, as it avoids the use of a needle and syringe. Mucosal vaccine administration …

Intranasal vaccination by directly applying a vaccine dry powder is appealing. However, a
method that can be used to transform a vaccine from a liquid to a dry powder and a device …

The vast majority of pathogens enter the human body via the mucosal surfaces of the
gastrointestinal, respiratory, and urogenital tracts, where they initiate mucosal infections that …

The mucosal surface is the largest route through which pathogens enter the human body. To
control the outbreak of mucosal infectious diseases, we must use our knowledge of the …

For centuries, intranasal administration has been a perennial fascination for humanity. In
recent times, the realm of nanotechnology-based biomaterials has witnessed a notable …