This chapter describes the implication of oxidative stress in the progression of the liver
diseases with higher prevalence worldwide: nonalcoholic fatty liver disease, cholestasis …

The liver is an organ that is particularly exposed to reactive oxygen species (ROS), which
not only arise during metabolic functions but also during the biotransformation of …

The liver plays a central role in the biotransformation of a variety of drugs and xenobiotics.
During the biotransformation of drugs and chemicals, the liver generates various reactive …

Oxygen is vital for life as it is required for many different enzymatic reactions involved in
intermediate metabolism and xenobiotic biotransformation. Moreover, oxygen consumption …

Redox state constitutes an important background of numerous liver disorders. The redox
state participates in the course of inflammatory, metabolic and proliferative liver diseases …

Oxidative stress and inflammation are hallmarks of virtually all (chronic) liver diseases. Not
surprisingly, understanding the role of oxidative stress and its deleterious consequences …

Oxidative stress and liver injury are strongly associated. Oxidative stress in the liver can be
triggered during different conditions and by specific etiologies, including hepatotoxins …

Background: Redox state is a significant contributor to the backdrop of many liver illnesses.
Inflammatory, metabolic, and proliferative liver diseases all involve the redox state. The …

Oxidative stress is importantly involved in the pathophysiology of various liver diseases. The
redox state participates on the course of the inflammatory, metabolic and proliferative liver …

The increased production of derivatives of molecular oxygen and nitrogen in the form of
reactive oxygen species (ROS) and reactive nitrogen species (RNS) lead to molecular …