Diseases originating from altered energy homeostasis including obesity, and type 2
diabetes are rapidly increasing worldwide. Research in the last few decades on animal …

Besides its role as an energy storage organ, adipose tissue can be viewed as a dynamic
and complex endocrine organ, which produces and secretes several adipokines, including …

Adipokines are proteins secreted by adipose tissue to regulate glucolipid metabolism and
play vital roles in our body. Different adipokines have more than one endocrine function and …

Obesity plays a causative role in the pathogenesis of the metabolic syndrome. Adipokines
may link obesity to its co-morbidities. Most adipokines with pro-inflammatory properties are …

For many years, adipose tissue was considered as an inert energy storage organ that
accumulates and stores triacylglycerols during energy excess and releases fatty acids in …

Adipose tissue is an extremely active organ, and plays a fundamental role in the genesis of
comorbidities associated with obesity. Since the discovery of leptin, an important focus has …

The worldwide epidemic of obesity has brought considerable attention to research aimed at
understanding the biology of adipocytes (fat cells) and the events occurring in adipose …

Increasing evidence shows that obesity is the critical factor in shaping cardio-metabolic
phenotypes. However, the pathogenic mechanisms remain incompletely clarified. According …

With the increasing prevalence of obesity, obesity-related problems such as cardiometabolic
disorders (CMD), are also rapidly increasing. To prevent and alleviate the progressive …

Disentangling the neuroendocrine systems, which regulate energy homeostasis and
adiposity, has been a long-standing challenge in pathophysiology, with obesity as an …