Individualized thromboprophylaxis in patients with lower-leg cast immobilization—a validation and subgroup analysis in the POT-CAST trial

B Nemeth, R van Adrichem, R Nelissen… - Thrombosis and …, 2019 - thieme-connect.com
Background A small subgroup of patients treated with lower-leg cast immobilization
develops venous thromboembolism (VTE). Objectives (1) Identify risk factors for VTE in …

[HTML][HTML] High risk of recurrent venous thrombosis in patients with lower‐leg cast immobilization

B Nemeth, JF Timp, A van Hylckama Vlieg… - Journal of Thrombosis …, 2018 - Elsevier
Essentials• The risk of recurrent venous thrombosis (VT) after leg‐cast in patients with prior
VT is unknown.• In a nested case‐control study within the MEGA follow‐up study we aimed …

Venous thrombosis risk after cast immobilization of the lower extremity: derivation and validation of a clinical prediction score, L-TRiP (cast), in three population-based …

B Nemeth, RA Adrichem, A Hylckama Vlieg… - PLoS …, 2015 - journals.plos.org
Background Guidelines and clinical practice vary considerably with respect to thrombosis
prophylaxis during plaster cast immobilization of the lower extremity. Identifying patients at …

The incidence of deep vein thrombosis and pulmonary embolism following cast immobilisation and early functional bracing of Tendo Achilles rupture without …

GJ Heyes, A Tucker, ALR Michael… - European Journal of …, 2015 - Springer
Purpose The routine use of thromboprophylaxis during cast immobilisation for lower leg
trauma is controversial. The concern involves the perceived increased risk of deep vein …

Thromboprophylaxis in patients with lower limb immobilisation–review of current status

TJC Nokes, J Keenan - British journal of haematology, 2009 - Wiley Online Library
The risk for venous thromboembolism (VTE) associated with lower limb immobilisation is
unclear, owing to of a lack of evidence from studies in this patient group. However, six small …

A critical evaluation of venous thromboembolism risk assessment models used in patients with lower limb cast immobilisation

U Watson, BA Hickey, HM Jones, A Perera - Foot and Ankle Surgery, 2016 - Elsevier
Background There is a recognised link between lower limb cast immobilisation and the
development of venous thromboembolism (VTE). Our aim was to assess the diagnostic …

Should orthopedic outpatients with lower limb casts be given deep vein thrombosis prophylaxis?

S Thomas, M Van Kampen - Clinical and applied thrombosis …, 2011 - journals.sagepub.com
Aim: This study was undertaken to assess the incidence of symptomatic deep vein
thrombosis (DVT) in orthopedic outpatients who are treated with lower limb casts and were …

Development of the plymouth VTe risk score for patients treated with lower limb immobilisation in a cast or boot

J Keenan, H Rowswell, TJC Nokes - Injury, 2021 - Elsevier
There is approximately a 2% risk of clinically significant VTE following temporary lower limb
immobilisation after injury with an ankle immobilising plaster cast or boot. There is evidence …

[HTML][HTML] Prevention of venous thromboembolism in patients with immobilization of the lower extremities: a meta‐analysis of randomized controlled trials

HB Ettema, BJ Kollen, C Verheyen, HR Büller - Journal of thrombosis and …, 2008 - Elsevier
Background: It is controversial whether the prevention of venous thromboembolism (VTE) in
patients with lower‐leg immobilization is necessary. Objectives: To assess the benefits and …

[HTML][HTML] Below‐knee cast immobilization and the risk of venous thrombosis: results from a large population‐based case–control study

RA Van Adrichem, J Debeij, R Nelissen… - Journal of thrombosis …, 2014 - Elsevier
Background From the available evidence, the risk of venous thrombosis in patients with
below‐knee cast immobilization remains unclear. Objectives To estimate the risk of venous …