[HTML][HTML] Opiorphin as a biomarker of orofacial conditions: a meta-analysis

AL Porporatti, CA de Oliveira Machado, I Alajbeg… - Scientific reports, 2023 - nature.com
The aim of this meta-analysis was to answer the following question:“Are there any
differences in opiorphin biomarker concentrations between different orofacial conditions and …

[PDF][PDF] Quantitative analysis and expression of salivary opiorphin in painful oral soft-tissue conditions: A descriptive study

NK Nejad, KA RP, S Sujatha - J Global Oral Health, 2020 - researchgate.net
Objectives: Opiorphin is an enkephalinase inhibitor which suppresses pain by acting on the
opioid system. The levels of opiorphin in plasma and saliva have shown to vary in patients …

Salivary opiorphin in dental pain: A potential biomarker for dental disease

MS Ozdogan, M Gungormus, SI Yusufoglu… - Archives of Oral …, 2019 - Elsevier
Objectives Opiorphin is a recently discovered peptide shown to inhibit the enkephalin-
degrading enzymes and prolong the effects of enkephalins. Although opiorphin is found in …

A study of salivary opiorphin levels using different anesthetic drugs and techniques–A randomized controlled clinical study

SK Parida, T Guruprasad, VB Krishnakumar… - Journal of stomatology …, 2018 - Elsevier
Purpose This study aimed at assessing the change in salivary opiorphin levels before and
after administration of local anesthesia, with the use of three different local anesthetic …

Salivary Opiorphin is Dependent of Pain Intensity in Chronic TMD Patients

IZ Alajbeg, E Vrbanović, L Brkljačić, A Ivan - CED-IADR/NOF Oral Health …, 2019 - croris.hr
Objectives Opiorphin is pentapeptide that inhibits pain perception in humans. It can be
isolated from body fluids, including saliva. The cause of temporomandibular disorders …

Salivary opiorphin levels in denture‐related traumatic ulcers

MS Ozdogan, M Gungormus - Oral Diseases, 2023 - Wiley Online Library
Objective Opiorphin is a pentapeptide secreted in saliva and has a strong analgesic effect.
Salivary opiorphin has been shown to increase in orofacial pain and may act as a pain …

CHANGE IN OPIORPHIN LEVELS IN SALIVA AFTER CAPSAICIN STIMULATION-COMPARISON OF OROFACIAL PAIN PATIENTS AND THE CONTROLS.

I Orabović, K Naka, A Mrla… - Acta Stomatologica …, 2023 - search.ebscohost.com
Aim: The aim of the study was to compare the intensity of burning pain sensation and
salivary opiorphin levels after stimulation with capsaicin in burning mouth syndrome (BMS) …

Opiorphin in burning mouth syndrome patients: a case-control study

I Salarić, M Sabalić, I Alajbeg - Clinical Oral Investigations, 2017 - Springer
Objectives Opiorphin is a pentapeptide isolated from human saliva that suppresses pain
from chemically induced inflammation and acute physical pain. Burning mouth syndrome …

[HTML][HTML] Assessment of salivary opiorphin in oral lichen planus

Z Dalirsani, M Amirchaghmaghi, A Ghazi… - Brazilian Journal of …, 2024 - SciELO Brasil
Opiorphin is a pentapeptide, which could be isolated from human fluids and has a
decreasing effect on pain. Aim Since lichen planus is a chronic mucocutaneous disease …

Development and validation of a liquid chromatography–tandem mass spectrometry method for the quantification of opiorphin in human saliva

L Brkljačić, M Sabalić, I Salarić, I Jerić, I Alajbeg… - … of Chromatography B, 2011 - Elsevier
Opiorphin, QRFSR-peptide, is a mature product of the PROL1 (proline rich, lacrimal 1)
protein that showed beneficial effects in pain management, antidepressant-like actions as …