Background: Diabetes Mellitus (DM) is a multisystemic disease involving the homeostasis of
insulin secretion by the pancreatic islet beta cells (β-cells). It is associated with hypertension …

Type 1 diabetes (T1D) is the result of selective destruction of the insulin-producing β-cells in
the pancreatic islets of Langerhans. T1D is due to a complex interplay between the β-cell …

Diabetes mellitus is a complex multi-system disorder that may be classified as autoimmune
mediated type 1 diabetes, or as insulin resistance associated type 2 diabetes. In type 1 …

Type 1 diabetes is a polygenic, multifactorial autoimmune disease characterized by
selective and irreversible destruction of the insulin-producing β-cells in the pancreatic islets …

Abstract Diabetes mellitus type 1 (DM1) is a major public health problem that continues to
burden the healthcare systems worldwide, costing exponentially more as the epidemic …

The incidence of diabetes mellitus is growing rapidly, with an increasing disease related
morbidity and mortality. This is caused by macro‐and microvascular complications, as a …

Type 2 diabetes is a worldwide disease reaching epidemic dimensions. The rapid
progression of the disease urgently calls for both a broader and deeper understanding of its …

Gestational diabetes mellitus is a progressive and complex pregnancy complication, which
threatens both maternal and fetal health. It is urgent to screen for specific biomarkers for …

Diabetes, a multifactorial disorder is characterized by elevated blood glucose levels
resulting from changes in lifestyle, genetic and epigenetic changes or aberrations in …

Blood markers other than islet autoantibodies are greatly needed to indicate the pancreatic
beta cell destruction process as early as possible, and more accurately reflect the …