Discogenic low back pain is a serious medical and social problem, and accounts for 26%-
42% of the patients with chronic low back pain. Recent studies found that the pathologic …

Discogenic back pain is multifactorial; hence, physicians often struggle to identify the
underlying source of the pain. As a result, discogenic back pain is often hard to treat—even …

An estimated 40% of chronic lumbosacral spinal pain is attributed to the discus
intervertebralis. Degenerative changes following loss of hydration of the nucleus pulposus …

Discogenic low back pain is a common cause of disability, but its pathogenesis is poorly
understood. We collected 19 specimens of lumbar intervertebral discs from 17 patients with …

Abstract Purpose of Review Many studies have demonstrated that discogenic low back pain
is the most common type of chronic low back pain (CLBP), one of the major causes of …

Internal disc disruption is a common cause of disabling low back pain in a substantial
number of young, healthy adults. Crock described this painful entity and reported annular …

Background context Pain innate to intervertebral disc, often referred to as discogenic pain, is
suspected by some authors to be the major source of chronic low back and neck pain …

Low back pain (LBP) is very prevalent in the general population. Treatment of nonradicular
back pain, in the absence of deformity, continues to be controversial. Recently, anatomic …

Background context Although explored in humans and animal models, the
pathomechanisms of discogenic low back pain (LBP) remain unknown. Purpose The aim of …

Diagnosis and treatment of lumbar discogenic pain due to internal disc disruption (IDD)
remains a challenge. It accounts for 39% of patients with low back pain. The mechanism of …