Establishing a Novel Gene Signature Related to Histone Modifications for Predicting Prognosis in Lung Adenocarcinoma

M Liu, X Yu, S Xu, C Qu - Journal of Oncology, 2022 - Wiley Online Library
Background. Epigenetic modifications have been revealed to play an important role in
tumorigenesis and tumor development. This study aims to analyze the role of histone …

[HTML][HTML] A novel epithelial-mesenchymal transition-related gene signature for prognosis prediction in patients with lung adenocarcinoma

S Feng, C Huang, L Guo, H Wang, H Liu - Heliyon, 2022 - cell.com
Traditional pathological diagnoses and clinical methods are insufficient to accurately predict
the prognosis of lung adenocarcinoma (LUAD). Epithelial-mesenchymal transition (EMT) …

[HTML][HTML] Integrated single-cell and transcriptome sequencing analyses determines a chromatin regulator-based signature for evaluating prognosis in lung …

Q Shi, S Han, X Liu, S Wang, H Ma - Frontiers in oncology, 2022 - frontiersin.org
Background Accumulating evidence has highlighted the significance of chromatin regulator
(CR) in pathogenesis and progression of cancer. However, the prognostic role of CRs in …

[HTML][HTML] Identification of lung adenocarcinoma subtypes and a prognostic signature based on activity changes of the hallmark and immunologic gene sets

SK Zhou, DH Zeng, MQ Zhang, MM Chen, YM Liu… - Heliyon, 2024 - cell.com
Background Lung adenocarcinoma (LUAD) has a complex tumor heterogeneity. Our
research attempts to clearness LUAD subtypes and build a reliable prognostic signature …

[HTML][HTML] A prognostic signature model for unveiling tumor progression in lung adenocarcinoma

Z Li, T Zeng, C Zhou, Y Chen, W Yin - Frontiers in Oncology, 2022 - frontiersin.org
A more accurate prognosis is important for clinical treatment of lung adenocarcinoma.
However, due to the limitation of sample and technical bias, most prognostic signatures …

[HTML][HTML] A robust six-gene prognostic signature based on two prognostic subtypes constructed by chromatin regulators is correlated with immunological features and …

Q Chen, H Zhao, J Hu - Aging (Albany NY), 2023 - ncbi.nlm.nih.gov
Accumulating evidence has demonstrated that chromatin regulators (CRs) regulate immune
cell infiltration and are correlated with prognoses of patients in some cancers. However, the …

A gene expression-based immune signature for lung adenocarcinoma prognosis

L Wang, X Luo, C Cheng, CI Amos, G Cai… - Cancer Immunology …, 2020 - Springer
Background Lung adenocarcinoma (LUAD) has become the most frequent histologic type of
lung cancer in the past several decades. Recent successes with immune checkpoint …

Systematic profiling of immune signatures identifies prognostic predictors in lung adenocarcinoma

S Mao, Y Li, Z Lu, Y Che, J Huang, Y Lei, Y Wang… - Cellular Oncology, 2020 - Springer
Purpose Lung adenocarcinoma (LUAD) is the predominant subtype of lung cancer, with
increasing evidence showing clinical benefits of immunotherapy. However, a lack of …

Expression of Immunogenic Cell Death-Related Genes is Correlated with Immune Microenvironment and Predicts Prognosis in Lung Adenocarcinoma

W Gong, F Gao, F Shao, L Chen, Y Gao, J He - 2023 - researchsquare.com
Immunogenic cell death (ICD) is a type of regulated cell death that is enough to primes
adaptive immune response. Mounting evidence has demonstrated that ICD has the potential …

[HTML][HTML] Myeloid cell differentiation-related gene signature for predicting clinical outcome, immune microenvironment, and treatment response in lung adenocarcinoma

D Wu, Y Liu, J Liu, L Ma, X Tong - Scientific Reports, 2024 - nature.com
Considering the key role of myeloid cell differentiation—related genes in the tumor
microenvironment (TME), we aimed to build a prognostic risk model using these genes for …