Establishing a Novel Gene Signature Related to Histone Modifications for Predicting Prognosis in Lung Adenocarcinoma
M Liu, X Yu, S Xu, C Qu - Journal of Oncology, 2022 - Wiley Online Library
Background. Epigenetic modifications have been revealed to play an important role in
tumorigenesis and tumor development. This study aims to analyze the role of histone …
tumorigenesis and tumor development. This study aims to analyze the role of histone …
[HTML][HTML] A novel epithelial-mesenchymal transition-related gene signature for prognosis prediction in patients with lung adenocarcinoma
Traditional pathological diagnoses and clinical methods are insufficient to accurately predict
the prognosis of lung adenocarcinoma (LUAD). Epithelial-mesenchymal transition (EMT) …
the prognosis of lung adenocarcinoma (LUAD). Epithelial-mesenchymal transition (EMT) …
[HTML][HTML] Integrated single-cell and transcriptome sequencing analyses determines a chromatin regulator-based signature for evaluating prognosis in lung …
Q Shi, S Han, X Liu, S Wang, H Ma - Frontiers in oncology, 2022 - frontiersin.org
Background Accumulating evidence has highlighted the significance of chromatin regulator
(CR) in pathogenesis and progression of cancer. However, the prognostic role of CRs in …
(CR) in pathogenesis and progression of cancer. However, the prognostic role of CRs in …
[HTML][HTML] Identification of lung adenocarcinoma subtypes and a prognostic signature based on activity changes of the hallmark and immunologic gene sets
SK Zhou, DH Zeng, MQ Zhang, MM Chen, YM Liu… - Heliyon, 2024 - cell.com
Background Lung adenocarcinoma (LUAD) has a complex tumor heterogeneity. Our
research attempts to clearness LUAD subtypes and build a reliable prognostic signature …
research attempts to clearness LUAD subtypes and build a reliable prognostic signature …
[HTML][HTML] A prognostic signature model for unveiling tumor progression in lung adenocarcinoma
Z Li, T Zeng, C Zhou, Y Chen, W Yin - Frontiers in Oncology, 2022 - frontiersin.org
A more accurate prognosis is important for clinical treatment of lung adenocarcinoma.
However, due to the limitation of sample and technical bias, most prognostic signatures …
However, due to the limitation of sample and technical bias, most prognostic signatures …
[HTML][HTML] A robust six-gene prognostic signature based on two prognostic subtypes constructed by chromatin regulators is correlated with immunological features and …
Q Chen, H Zhao, J Hu - Aging (Albany NY), 2023 - ncbi.nlm.nih.gov
Accumulating evidence has demonstrated that chromatin regulators (CRs) regulate immune
cell infiltration and are correlated with prognoses of patients in some cancers. However, the …
cell infiltration and are correlated with prognoses of patients in some cancers. However, the …
A gene expression-based immune signature for lung adenocarcinoma prognosis
Background Lung adenocarcinoma (LUAD) has become the most frequent histologic type of
lung cancer in the past several decades. Recent successes with immune checkpoint …
lung cancer in the past several decades. Recent successes with immune checkpoint …
Systematic profiling of immune signatures identifies prognostic predictors in lung adenocarcinoma
S Mao, Y Li, Z Lu, Y Che, J Huang, Y Lei, Y Wang… - Cellular Oncology, 2020 - Springer
Purpose Lung adenocarcinoma (LUAD) is the predominant subtype of lung cancer, with
increasing evidence showing clinical benefits of immunotherapy. However, a lack of …
increasing evidence showing clinical benefits of immunotherapy. However, a lack of …
Expression of Immunogenic Cell Death-Related Genes is Correlated with Immune Microenvironment and Predicts Prognosis in Lung Adenocarcinoma
W Gong, F Gao, F Shao, L Chen, Y Gao, J He - 2023 - researchsquare.com
Immunogenic cell death (ICD) is a type of regulated cell death that is enough to primes
adaptive immune response. Mounting evidence has demonstrated that ICD has the potential …
adaptive immune response. Mounting evidence has demonstrated that ICD has the potential …
[HTML][HTML] Myeloid cell differentiation-related gene signature for predicting clinical outcome, immune microenvironment, and treatment response in lung adenocarcinoma
D Wu, Y Liu, J Liu, L Ma, X Tong - Scientific Reports, 2024 - nature.com
Considering the key role of myeloid cell differentiation—related genes in the tumor
microenvironment (TME), we aimed to build a prognostic risk model using these genes for …
microenvironment (TME), we aimed to build a prognostic risk model using these genes for …
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