[HTML][HTML] Lysophosphatidic acid receptor 6 (LPAR6) is a potential biomarker associated with lung adenocarcinoma

J He, R Gao, M Meng, M Yu, C Liu, J Li, Y Song… - International Journal of …, 2021 - mdpi.com
LPAR6 is the most recently determined G-protein-coupled receptor of the lysophosphatidic
acid receptor, and very few of studies have demonstrated the performance of LPAR6 in …

[PDF][PDF] LPAR5 stimulates the malignant progression of non-small-cell lung carcinoma by upregulating MLLT11.

HP Zhang, QK Chen, JF Xu - European Review for Medical & …, 2020 - europeanreview.org
OBJECTIVE: This study aims to explore the diagnostic and prognostic values of
Lysophosphatidic acid receptor 5 (LPAR5) in non-small-cell lung cancer (NSCLC) and its …

Lysophosphatidic acid receptor 6 (LPAR6) expression and prospective signaling pathway analysis in breast cancer

K Tao, S Guo, R Chen, C Yang, L Jian, H Yu… - Molecular Diagnosis & …, 2019 - Springer
Abstract Background and Objective Lysophosphatidic acid (LPA) has widely been reported
to participate in the numerous biological behaviors of tumors through its receptors. LPA …

Lysophosphatidic acid receptor 6 regulated by miR-27a-3p attenuates tumor proliferation in breast cancer

J Lei, S Guo, K Li, J Tian, B Zong, T Ai, Y Peng… - Clinical and …, 2022 - Springer
Purpose Lysophosphatidic acid (LPA) is a bioactive molecule which participates in many
physical and pathological processes. Although LPA receptor 6 (LPAR6), the last identified …

[HTML][HTML] LPAR1, correlated with immune infiltrates, is a potential prognostic biomarker in prostate cancer

J Shi, D Jiang, S Yang, X Zhang, J Wang, Y Liu… - Frontiers in …, 2020 - frontiersin.org
Prostate cancer is a common malignancy in men worldwide. Lysophosphatidic acid receptor
1 (LPAR1) is a critical gene and it mediates diverse biologic functions in tumor. However, the …

A distinctive protein signature induced by lysophosphatidic acid receptor 6 (LPAR6) expression in hepatocellular carcinoma cells

R Lippolis, D Gnocchi, L Santacroce… - Biochemical and …, 2020 - Elsevier
Hepatocellular carcinoma (HCC) is the most commonly diagnosed liver malignancy, ranking
third in the overall global cancer-related mortality. A complex network of interacting proteins …

LPAR2-mediated action promotes human renal cell carcinoma via MAPK/NF-κB signaling to regulate cytokine network

Y Wang, Z Qi, Z Li, S Bai, A Damirin - Journal of Cancer Research and …, 2023 - Springer
Purpose Lysophosphatidic acid (LPA) exerts various physiological and pathological effects
by activating its distinct G-protein-coupled LPA receptors. We demonstrated that LPA can …

Disruption of LPA‐LPAR1 pathway results in lung tumor growth inhibition by downregulating B7‐H3 expression in fibroblasts

F Meng, Z Yin, F Lu, W Wang, H Zhang - Thoracic Cancer, 2024 - Wiley Online Library
Abstract Background Lysophosphatidic acids (LPAs) belong to a class of bioactive
lysophospholipids with multiple functions including immunomodulatory roles in tumor …

Paradoxical downregulation of LPAR3 exerts tumor-promoting activity through autophagy induction in Ras-transformed cells

SH Hwang, HG Kim, M Lee - BMC cancer, 2022 - Springer
Background Lysophosphatidic acid receptor 3 (LPAR3) is coupled to G α i/o and G α 11/q
signaling. Previously, we reported that LPAR3 is highly methylated in carcinogen-induced …

[HTML][HTML] A novel prognostic biomarker LPAR6 in hepatocellular carcinoma via associating with immune infiltrates

J He, M Meng, H Wang - Journal of Clinical and Translational …, 2022 - ncbi.nlm.nih.gov
Methods The expression of LPAR6 and its clinical characteristics were evaluated on various
databases. The association between LPAR6 and immune infiltrates of various types of …