Autoimmune diseases, which comprise over 80 clinically distinct conditions, are
characterized by the presence of autoantibodies or autoreactive T cells directed against self …

Autoantibodies to intracellular constituents often occur naturally. This would be difficult to
understand were they unable to penetrate live cells, as was once generally accepted; …

Natural Autoantibodies provides an in-depth analysis of all aspects of natural antibodies.
The book examines the advantages and pitfalls of every type of technique that is widely …

Understanding the mechanisms of human autoimmune rheumatic diseases presents a
major challenge, due to marked complexity involving multiple domains, including genetics …

It is well recognised that a state of autoimmunity, in which immunological tolerance is
broken, precedes the development of symptoms in the majority of patients with rheumatoid …

Autoimmunity is a normal event, while autoimmune diseases result from an aberration of this
normal phenomenon. The etiology of this switch is considered multifactorial with the final …

Disease associated autoantibodies (AAB) are important biomarkers not only to confirm the
diagnosis of the respective systemic autoimmune disease but also to diagnose the disease …

Autoimmunity can be triggered by many environmental factors, among which infectious
agents are pivotal. Here, we summarize current knowledge of the relationship between …

Natural autoantibodies/natural autoimmunity forms a network that serves to protect the
organism from outer and inner danger but may also contribute to autoimmune disease. This …

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