Transplantation of rat cranial bone-derived mesenchymal stem cells promotes functional recovery in rats with spinal cord injury

Y Maeda, T Otsuka, M Takeda, T Okazaki, K Shimizu… - Scientific reports, 2021 - nature.com
Cell-based therapy using mesenchymal stem cells (MSCs) is a novel treatment strategy for
spinal cord injury (SCI). MSCs can be isolated from various tissues, and their characteristics …

Motor recovery after transplantation of bone marrow mesenchymal stem cells in rat models of spinal cord injury

DM Muniswami, P Kanthakumar… - Annals of …, 2019 - karger.com
Background: Neuronal tissue has a limited potential to self-renew or get repaired after
damage. Cell therapies using stem cells are promising approaches for the treatment of …

Implantation of BM mesenchymal stem cells into injured spinal cord elicits de novo neurogenesis and functional recovery: evidence from a study in rhesus monkeys

YB Deng, XG Liu, ZG Liu, XL Liu, Y Liu, GQ Zhou - Cytotherapy, 2006 - Taylor & Francis
Background Transplantation of mesenchymal stem cells (MSC) in rodent models has proved
to be an effective therapeutic approach for spinal cord injury (SCI). However, further studies …

Comparisons of neurotrophic effects of mesenchymal stem cells derived from different tissues on chronic spinal cord injury rats

T Otsuka, Y Maeda, T Kurose, K Nakagawa… - Stem Cells and …, 2021 - liebertpub.com
Cell-based therapies with mesenchymal stem cells (MSCs) are considered as promising
strategies for spinal cord injury (SCI). MSCs have unique characteristics due to differences …

Roles of mesenchymal stem cells in spinal cord injury

J Qu, H Zhang - Stem cells international, 2017 - Wiley Online Library
Spinal cord injury (SCI) represents one of the most complicated and heterogeneous
pathological processes of central nervous system (CNS) impairments, which is still beyond …

[HTML][HTML] Multiple strategies enhance the efficacy of MSCs transplantation for spinal cord injury

QM Pang, KQ Deng, M Zhang, XC Wu, RL Yang… - Biomedicine & …, 2023 - Elsevier
Spinal cord injury (SCI) is a serious complication of the central nervous system (CNS) after
spine injury, often resulting in severe sensory, motor, and autonomic dysfunction below the …

Attenuating spinal cord injury by conditioned medium from bone marrow mesenchymal stem cells

MJ Tsai, DY Liou, YR Lin, CF Weng, MC Huang… - Journal of clinical …, 2018 - mdpi.com
Spinal cord injury (SCI) is a devastating neurological condition and might even result in
death. However, current treatments are not sufficient to repair such damage. Bone marrow …

Conditioned medium from bone marrow-derived mesenchymal stem cells improves recovery after spinal cord injury in rats: an original strategy to avoid cell …

D Cantinieaux, R Quertainmont, S Blacher, L Rossi… - PloS one, 2013 - journals.plos.org
Spinal cord injury triggers irreversible loss of motor and sensory functions. Numerous
strategies aiming at repairing the injured spinal cord have been studied. Among them, the …

Therapeutic efficacy of human mesenchymal stem cells with different delivery route and dosages in rat models of spinal cord injury

G Liu, Z Zhao, H Wang, C Hao, W Wang… - Cell …, 2022 - journals.sagepub.com
Recent studies have shown that the use of mesenchymal stem/stromal cells (MSCs) may be
a promising strategy for treating spinal cord injury (SCI). This study aimed to explore the …

Neuroprotective effects of human umbilical cord-derived mesenchymal stem cells from different donors on spinal cord injury in mice

X Zhu, Z Wang, YE Sun, Y Liu, Z Wu, B Ma… - Frontiers in Cellular …, 2022 - frontiersin.org
Spinal cord injury (SCI) is caused by an external force, leading to severe dysfunction of the
limbs below the injured segment. The inflammatory response plays a vital role in the …