Diabetic nephropathy is a leading cause of end stage renal disease and its occurance is
increasing worldwide. The most effective treatment strategy for the condition is intensive …

Autophagy plays a crucial role in cellular homeostasis through the degradation and
recycling of organelles such as mitochondria or endoplasmic reticulum (ER) that are closely …

Type 2 diabetes mellitus is characterized by insulin resistance and failure of pancreatic β-
cells producing insulin. Autophagy plays a crucial role in cellular homeostasis through …

Despite recent advancements in clinical drugs, diabetes treatment still needs further
progress. As such, ongoing research has attempted to determine the precise molecular …

T1D (type 1 diabetes) is an autoimmune disease characterized by lymphocytic infiltration, or
inflammation in pancreatic islets called 'insulitis.'Comparatively speaking, T2D (type 2 …

Autophagy is a major catabolic pathway by which mammalian cells degrade and recycle
macromolecules and organelles. It plays a critical role in removing protein aggregates, as …

Autophagy, a conserved catabolic process, plays an immensely significant role in a variety
of diseases. However, whether it imparts a protective function in diseases remains …

Diabetic nephropathy is a leading cause of end‐stage renal disease worldwide. The
multipronged drug approach targeting blood pressure and serum levels of glucose, insulin …

Diabetic nephropathy (DN) is the most common cause of end-stage kidney disease
worldwide, and is associated with increased morbidity and mortality in patients with both …

Obesity is a direct result of the accumulation of white adipose tissue (WAT). In this study, the
role of autophagy in the differentiation of white adipose tissue was studied by deleting the …