Curcumin for malaria therapy
RC Reddy, PG Vatsala, VG Keshamouni… - Biochemical and …, 2005 - Elsevier
Malaria remains a major global health concern. New, inexpensive, and effective antimalarial
agents are urgently needed. Here we show that curcumin, a polyphenolic organic molecule …
agents are urgently needed. Here we show that curcumin, a polyphenolic organic molecule …
Synthesis and exploration of novel curcumin analogues as anti-malarial agents
Curcumin, a major yellow pigment and active component of turmeric, has been shown to
possess anti-inflammatory and anti-cancer activities. Recent studies have indicated that …
possess anti-inflammatory and anti-cancer activities. Recent studies have indicated that …
[HTML][HTML] Cellular Effects of Curcumin on Plasmodium falciparum Include Disruption of Microtubules
R Chakrabarti, PS Rawat, BM Cooke, RL Coppel… - PLoS …, 2013 - journals.plos.org
Curcumin has been widely investigated for its myriad cellular effects resulting in reduced
proliferation of various eukaryotic cells including cancer cells and the human malaria …
proliferation of various eukaryotic cells including cancer cells and the human malaria …
Cytotoxic Effect of Curcumin on Malaria Parasite Plasmodium falciparum: Inhibition of Histone Acetylation and Generation of Reactive Oxygen Species
L Cui, J Miao, L Cui - Antimicrobial agents and chemotherapy, 2007 - Am Soc Microbiol
The emergence of multidrug-resistant parasites is a major concern for malaria control, and
development of novel drugs is a high priority. Curcumin, a natural polyphenolic compound …
development of novel drugs is a high priority. Curcumin, a natural polyphenolic compound …
Curcumin-artemisinin combination therapy for malaria
DN Nandakumar, VA Nagaraj… - Antimicrobial agents …, 2006 - Am Soc Microbiol
Artemisinin and curcumin show an additive interaction in killing Plasmodium falciparum in
culture. In vivo, 3 oral doses of curcumin following a single injection of α, β-arteether to …
culture. In vivo, 3 oral doses of curcumin following a single injection of α, β-arteether to …
[HTML][HTML] Nanocurcumin is superior to native curcumin in preventing degenerative changes in Experimental Cerebral Malaria
Curcumin has many pharmacological activities despite its poor bioavailability and in vivo
stability. Here, we show that a nanoformulated curcumin (PLGA-curcumin) has better …
stability. Here, we show that a nanoformulated curcumin (PLGA-curcumin) has better …
[HTML][HTML] The plant-based immunomodulator curcumin as a potential candidate for the development of an adjunctive therapy for cerebral malaria
PN Mimche, D Taramelli, L Vivas - Malaria journal, 2011 - Springer
The clinical manifestations of cerebral malaria (CM) are well correlated with underlying
major pathophysiological events occurring during an acute malaria infection, the most …
major pathophysiological events occurring during an acute malaria infection, the most …
Curcumin and its analogues: a potential natural compound against HIV infection and AIDS
No safe and effective cure currently exists for human immunodeficiency virus (HIV).
However, antiretroviral therapy can prolong the lives of HIV patients and lowers the …
However, antiretroviral therapy can prolong the lives of HIV patients and lowers the …
Curcumin and curcumin-loaded nanoparticles: Antipathogenic and antiparasitic activities
Introduction: Curcumin is an important bioactive compound present in Curcuma longa, and
is well known for its bioactivities such as anti–inflammatory, anticancer, antimicrobial …
is well known for its bioactivities such as anti–inflammatory, anticancer, antimicrobial …
Latent activity of curcumin against leishmaniasis in vitro
MATERIALS AND METHODS Parasite Cultures All the promastigote cultures of both the
reference and local Pakistani leishmanial strains were maintained in blood agar based bi …
reference and local Pakistani leishmanial strains were maintained in blood agar based bi …