FLUORESCENT IMAGES OF MITOCHONDRIAL REDOX STATES IN IN SITU MOUSE HYPOXIC ISCHEMIC INTESTINES
We have imaged mitochondrial oxidation–reduction states by taking a ratio of mitochondrial
fluorophores: NADH (reduced nicotinamide adenine dinucleotide) to Fp (oxidized …
fluorophores: NADH (reduced nicotinamide adenine dinucleotide) to Fp (oxidized …
Quantitative redox scanning of tissue samples using a calibration procedure
HN Xu, B Wu, S Nioka, B Chance… - Journal of innovative …, 2009 - World Scientific
The fluorescence properties of reduced nicotinamide adenine dinucleotide (NADH) and
oxidized flavoproteins (Fp) including flavin adenine dinucleotide (FAD) in the respiratory …
oxidized flavoproteins (Fp) including flavin adenine dinucleotide (FAD) in the respiratory …
Mitochondrial redox imaging for cancer diagnostic and therapeutic studies
Mitochondrial redox states provide important information about energy-linked biological
processes and signaling events in tissues for various disease phenotypes including cancer …
processes and signaling events in tissues for various disease phenotypes including cancer …
Quantitative redox imaging biomarkers for studying tissue metabolic state and its heterogeneity
NAD+/NADH redox state has been implicated in many diseases such as cancer and
diabetes as well as in the regulation of embryonic development and aging. To …
diabetes as well as in the regulation of embryonic development and aging. To …
From identification of fluorescent flavoproteins to mitochondrial redox indicators in intact tissues
IE Hassinen - Journal of Innovative Optical Health Sciences, 2014 - World Scientific
Development of the use of flavin and nicotinamide-adenine nucleotide fluorescence in
monitoring the redox state of the free mitochondrial NADH/NAD+ couple in cells, tissues and …
monitoring the redox state of the free mitochondrial NADH/NAD+ couple in cells, tissues and …
Chop therapy induced mitochondrial redox state alteration in non-hodgkin's lymphoma xenografts
HN Xu, H Zhao, TA Mir, SC Lee, M Feng… - Journal of innovative …, 2013 - World Scientific
We are interested in investigating whether cancer therapy may alter the mitochondrial redox
state in cancer cells to inhibit their growth and survival. The redox state can be imaged by …
state in cancer cells to inhibit their growth and survival. The redox state can be imaged by …
Optical imaging of tissue mitochondrial redox state in intact rat lungs in two models of pulmonary oxidative stress
Ventilation with enhanced fractions of O 2 (hyperoxia) is a common and necessary treatment
for hypoxemia in patients with lung failure, but prolonged exposure to hyperoxia causes lung …
for hypoxemia in patients with lung failure, but prolonged exposure to hyperoxia causes lung …
Calibration of redox scanning for tissue samples
HN Xu, B Wu, S Nioka, B Chance… - Optical Tomography and …, 2009 - spiedigitallibrary.org
The fluorescence properties of reduced nicotinamide adenine dinucleotide (NADH) and
oxidized flavoproteins (Fp) such as flavin adenine dinucleotide (FAD) in the respiratory …
oxidized flavoproteins (Fp) such as flavin adenine dinucleotide (FAD) in the respiratory …
Optical redox imaging of lonidamine treatment response of melanoma cells and xenografts
Purpose Fluorescence of co-enzyme reduced nicotinamide adenine dinucleotide (NADH)
and oxidized flavoproteins (Fp) provides a sensitive measure of the mitochondrial redox …
and oxidized flavoproteins (Fp) provides a sensitive measure of the mitochondrial redox …
Optical imaging for the assessment of hepatocyte metabolic state in ischemia and reperfusion injuries
Deterioration in mitochondrial function leads to hepatic ischemia and reperfusion injury (IRI)
in liver surgery and transplantation. 3D optical cryoimaging was used to measure the levels …
in liver surgery and transplantation. 3D optical cryoimaging was used to measure the levels …