Daily and intermittent rosuvastatin 5 mg therapy in statin intolerant patients: an observational study

C Meek, AS Wierzbicki, C Jewkes… - … medical research and …, 2012 - Taylor & Francis
Objective: To examine the efficacy and tolerability of rosuvastatin 5 mg at daily and non-daily
dosing regimens. Research design and methods: A retrospective survey was conducted at …

Efficacy and tolerability of once-weekly rosuvastatin in patients with previous statin intolerance

SP Kennedy, GP Barnas, MJ Schmidt… - Journal of Clinical …, 2011 - Elsevier
BACKGROUND: Many patients who could benefit from hydroxymethylglutaryl coenzyme-A
reductase inhibitors (statins) are unable to take statins because of myalgias while taking …

Effects of once weekly rosuvastatin among patients with a prior statin intolerance

JM Backes, PM Moriarty, JF Ruisinger… - The American journal of …, 2007 - Elsevier
Statins possess an excellent safety profile and are generally well tolerated when
administered in the standard once-daily dosing regimen. A small percentage of patients …

Once-a-week rosuvastatin (2.5 to 20 mg) in patients with a previous statin intolerance

JF Ruisinger, JM Backes, CA Gibson… - The American journal of …, 2009 - Elsevier
The purpose of this study was to determine the efficacy of rosuvastatin dosed once a week in
patients with a previous statin adverse event. Rosuvastatin once a week was tolerated by 37 …

Efficacy of rosuvastatin (5 mg and 10 mg) twice a week in patients intolerant to daily statins

M Gadarla, AK Kearns, PD Thompson - The American journal of cardiology, 2008 - Elsevier
The aim of this study was to evaluate the efficacy of rosuvastatin twice weekly in 40 patients
intolerant to daily statins. Rosuvastatin twice weekly alone or added to other lipid-lowering …

Rosuvastatin 5 and 10 mg/d: a pilot study of the effects in hypercholesterolemic adults unable to tolerate other statins and reach LDL cholesterol goals with nonstatin …

CJ Glueck, D Aregawi, M Agloria, Q Khalil… - Clinical …, 2006 - Elsevier
BACKGROUND:: Patients with high levels of low-density lipoprotein cholesterol (LDL-C)
might not tolerate 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (“statins”) …

Safety of rosuvastatin: update on 16,876 rosuvastatin-treated patients in a multinational clinical trial program

J Shepherd, DG Vidt, E Miller, S Harris, J Blasetto - Cardiology, 2007 - karger.com
Background: The safety and tolerability of rosuvastatin were assessed using data from
16,876 patients who received rosuvastatin 5–40 mg in a multinational phase II/III/IIIb/IV …

Efficacy and safety of rosuvastatin every other day compared with once daily in patients with hypercholesterolemia

S Wongwiwatthananukit… - Annals of …, 2006 - journals.sagepub.com
Background: Although most patients with hypercholesterolemia require life-long therapy with
statins, these drugs are underused due to high costs. Every-other-day therapy could be one …

Rosuvastatin demonstrates greater reduction of low-density lipoprotein cholesterol compared with pravastatin and simvastatin in hypercholesterolaemic patients: a …

R Paoletti, M Fahmy, G Mahla… - Journal of …, 2001 - journals.sagepub.com
Background Rosuvastatin (Crestor), a new, highly efficacious statin, has demonstrated dose-
dependent low-density lipoprotein cholesterol (LDL-C) reductions of up to 65% in a dose …

Achieving 2003 European lipid goals with rosuvastatin and comparator statins in 6743 patients in real-life clinical practice: DISCOVERY meta-analysis

A Middleton, AS Binbrek, FAH Fonseca… - … medical research and …, 2006 - Taylor & Francis
Background: There is an increasing body of evidence to support the benefits of reducing low-
density lipoprotein cholesterol (LDL-C) levels and this has been reflected in a lowering of …