The human progesterone receptor (PR) is expressed as two isoforms, PRA and PRB, that
function as ligand-activated transcription factors. In vitro studies suggest that the isoforms …

The human progesterone receptor (PR) expressed as two isoforms, PRA and PRB, which
function as ligand-activated transcription factors. In-vitro studies suggest that the isoforms …

Progesterone plays a central role in the regulation of ovarian function. The progesterone
receptor (PR) has been shown to be essential for ovulation because mice lacking PR fail to …

Progesterone is a potent mitogen in the mammary gland. Based on studies using cells and
animals engineered to express progesterone receptor (PR) isoforms A or B, PRA and PRB …

In rodents, progesterone receptors (PRs) A and B have different and often nonoverlapping
roles, and this study asked whether different activities of the PR proteins in mouse are …

Progesterone receptor (PR) is expressed in a wide variety of human tissues, including both
reproductive and non-reproductive tissues. Upon binding to the PR, progesterone can …

Recent studies suggest that the progesterone receptor isoforms (PR-A and PR-B) activate
genes differentially and that PR-A may act as a repressor of PR-B function. Hence, the …

We previously demonstrated that 17β hydroxysteroid dehydrogenase type 2, the enzyme
that inactivates estradiol to estrone, is expressed in luteal eutopic endometrium in response …

The steroid hormone progesterone plays a central role in the reproductive events associated
with pregnancy establishment and maintenance. Physiological effects of progesterone are …

Objective: To study the functional differences between the two progesterone receptor
isoforms (hPRA and hPRB) in human endometrial cancer, two new endometrial carcinoma …