Hinge and amino-terminal sequences contribute to solution dimerization of human progesterone receptor

MJ Tetel, S Jung, P Carbajo, T Ladtkow… - Molecular …, 1997 - academic.oup.com
We and others have shown previously that progesterone receptors (PR) form homodimers in
solution in the absence of DNA and that dimers are the preferential form of receptor that …

Progesterone receptor isoform functions in normal breast development and breast cancer

A Kariagina, MD Aupperlee… - Critical Reviews™ in …, 2008 - dl.begellhouse.com
Progesterone acting through two isoforms of the progesterone receptor (PR), PRA and PRB,
regulates proliferation and differentiation in the normal mammary gland in mouse, rat, and …

Localization of progesterone receptor with monoclonal antibodies to the human progestin receptor

MF PRESS, GL GREENE - Endocrinology, 1988 - academic.oup.com
A series of rat and mouse monoclonal antibodies to the human progesterone receptor (PR)
has recently been produced. These antibodies were used for the immunocytochemical …

Molecular cloning, sequence analyses, and expression of complementary DNA encoding murine progesterone receptor

DR Schott, G Shyamala, W Schneider, G Parry - Biochemistry, 1991 - ACS Publications
Materials and Methods Description of Probes. The probe used for screening the cDNA
library, hPR54, was a gift from Dr. BW O'Malley and contained a 2.6-kb fragment of the …

An amino-terminal truncated progesterone receptor isoform, PRc, enhances progestin-induced transcriptional activity.

LL Wei, P Hawkins, C Baker, B Norris… - Molecular …, 1996 - academic.oup.com
Previously we reported the identification of two unique progesterone receptor (PR)
messenger RNA transcripts that encode a smaller PR isoform, termed the C-receptor (PRc) …

Identification of a phosphorylation site in the hinge region of the human progesterone receptor and additional amino-terminal phosphorylation sites

TA Knotts, RS Orkiszewski, RG Cook… - Journal of Biological …, 2001 - ASBMB
We have previously reported the identification of seven in vivo phosphorylation sites in the
amino-terminal region of the human progesterone receptor (PR). From our previous in vivo …

Differential hormonal regulation and function of progesterone receptor isoforms in normal adult mouse mammary gland

MD Aupperlee, SZ Haslam - Endocrinology, 2007 - academic.oup.com
In normal mouse mammary gland, the mitogenic action of progesterone (P) is mediated by
two P receptor (PR) isoforms, PRA and PRB. PRA is predominantly expressed in the adult …

Immunohistochemical analysis of human uterine estrogen and progesterone receptors throughout the menstrual cycle

BA LESSEY, AP KILLAM, DA METZGER… - The Journal of …, 1988 - academic.oup.com
Estrogen receptors (ER) and progesterone receptors (PgR) were studied
immunohistochemically using specific antireceptor monoclonal antibodies in uterine tissue …

Progesterone receptor isoforms expression pattern in the rat brain during the estrotts cycle

C Guerra-Araiza, MA Cerbón, S Morimoto… - Life sciences, 2000 - Elsevier
Progesterone receptor (PR) isoforms expression was determined in the hypothalamus, the
preoptic area, the hippocampus and the frontal cerebral cortex of the rat at 12: 00 h on each …

Two distinct estrogen‐regulated promoters generate transcripts encoding the two functionally different human progesterone receptor forms A and B.

P Kastner, A Krust, B Turcotte, U Stropp, L Tora… - The EMBO …, 1990 - embopress.org
The human progesterone receptor (hPR) cDNA, synthesized from T47D breast cancer cells,
and the hPR gene 5′‐flanking region were cloned and sequenced. Comparison of the …