Disruption of estrogen signaling does not prevent progesterone action in the estrogen receptor α knockout mouse uterus

SW Curtis, J Clark, P Myers… - Proceedings of the …, 1999 - National Acad Sciences
Estrogen is known to increase progesterone receptor (PR) levels in the wild-type mouse
uterus, and this estrogen induction was thought to be important for progesterone action …

Immunocytochemical localization of progesterone receptor in the reproductive tract of adult female rats

Y Ohta, T Sato, T Iguchi - Biology of reproduction, 1993 - academic.oup.com
The distribution of the progesterone receptor (PR) was investigated immunocytochemically
in female reproductive tracts of rats during the estrous cycle and early pregnancy through …

Hormone-dependent covalent modification and processing of human progesterone receptors in the nucleus

KB HORWITZ, MD FRANCIS, LL WEI - Dna, 1985 - liebertpub.com
In situ photoaffinity labeling, which minimizes in vitro incubations and proteolytic artifacts,
was used to study the structure of progesterone receptors (PR) in intact T47D human breast …

Differential regulation of the human progesterone receptor gene through an estrogen response element half site and Sp1 sites

LN Petz, YS Ziegler, JR Schultz, H Kim… - The Journal of steroid …, 2004 - Elsevier
The progesterone receptor (PR) gene is regulated by estrogen in normal reproductive
tissues and in MCF-7 human breast cancer cells. Although it is generally thought that …

Immunocytochemical study of mammalian progesterone receptor using monoclonal antibodies

M Perrot-Applanat, F Logeat, MT Groyer-Picard… - …, 1985 - academic.oup.com
Five monoclonal antibodies were used for the immunocytochemical study of mammalian
progesterone receptor (PR). Initial studies were aimed at defining the optimal experimental …

Effect of overexpression of progesterone receptor A on endogenous progestin-sensitive endpoints in breast cancer cells

EM McGowan, CL Clarke - Molecular Endocrinology, 1999 - academic.oup.com
The human progesterone receptor (PR) is expressed as two isoforms, PRA and PRB, which
differ in the N-terminal region and exhibit different activities in vitro, with PRA demonstrating …

Two pathways of progesterone action in the human endometrium: implications for implantation and contraception

BA Lessey - Steroids, 2003 - Elsevier
The endometrium is the site of implantation and pregnancy. Preparation for this important
biological event relies primarily on progesterone, which takes the estrogen-primed …

Distribution of the A and B forms of the progesterone receptor messenger ribonucleic acid and protein in uterine leiomyomata and adjacent myometrium.

B Viville, DS Charnock-Jones… - Human reproduction …, 1997 - academic.oup.com
The two forms of the progesterone receptor, PR-A and PR-B, are independently regulated at
the transcriptional level, and show distinct responses to progesterone antagonists. We were …

5′-Heterogeneity in human progesterone receptor transcripts predicts a new amino-terminal truncated “C”-receptor and unique A-receptor messages

LL Wei, C Gonzalez-Aller, WM Wood… - Molecular …, 1990 - academic.oup.com
Human progesterone receptors (PR) are thought to comprise two naturally occurring
hormone-binding proteins: 94-kDa A-receptors and 120-kDa B-receptors. In this paper we …

Post-translational modifications of the progesterone receptors

HA Abdel-Hafiz, KB Horwitz - The Journal of steroid biochemistry and …, 2014 - Elsevier
Progesterone plays a key role in the development, differentiation and maintenance of female
reproductive tissues and has multiple non-reproductive neural functions. Depending on the …