Systemic light chain (AL) amyloidosis is caused by a B-cell (most commonly plasma cell)
clone that produces a toxic light chain that forms amyloid fibrils in tissues and causes …

AL amyloidosis is a plasma cell disorder leading to the production and extracellular
deposition of abnormal immunoglobulin light chains called amyloid. The pathogenesis of the …

Light chain (AL) amyloidosis is a plasma cell dyscrasia that results in an overproduction of
immunoglobulins of the lambda or kappa light chains. These monoclonal ALs begin to form …

Introduction Amyloidosis is a very rare blood disease characterized by the production of
abnormal misfolded extracellular proteins that are deposited in body tissues or organs …

Systemic amyloid light chain amyloidosis is a protein conformation disorder caused by a
clonal plasma cell dyscrasia. Symptoms result from fibrillar extracellular deposits in kidney …

Immunoglobulinh light chain (AL) amyloidosis is a plasma cell dyscrasia characterized by
the overproduction and tissue deposition of monoclonal immunoglobulin light chains which …

Immunoglobulin amyloid light-chain (AL) amyloidosis is the most common form of systemic
amyloidosis, where the culprit amyloidogenic protein is immunoglobulin light chains …

Immunoglobulin light-chain (AL) amyloidosis is a systemic disease characterized by the
production and deposition of light chain-derived amyloid fibrils in different organs. Prompt …

Treatment with high-dose melphalan chemotherapy supported by hematopoietic rescue with
autologous stem cells produces high rates of hematologic responses and improvement in …

The recent decades have ushered in considerable advancements in the diagnosis and
treatment of systemic light chain (AL) amyloidosis. As disease outcomes improve, AL …