Genomic profiling of pediatric acute myeloid leukemia reveals a changing mutational landscape
from disease diagnosis to relapse Page 1 1 Genomic profiling of pediatric acute myeloid …

Little is known about the factors that affect treatment outcome in very young children with
acute myeloid leukemia (AML). We therefore analyzed the prognostic impact of various …

Acute myelogenous leukemia (AML) accounts for about 20% of the acute leukemias seen in
children. In contrast to childhood acute lymphoblastic leukemia (ALL), only modest …

Data on occurrence, genetic characteristics and prognostic impact of complex and
monosomal karyotype (CK/MK) in children with acute myeloid leukaemia (AML) are scarce …

Between 1993 and 2001, 318 children were diagnosed with acute myeloid leukaemia (AML)
in the Nordic countries. The patient group comprised 237 children< 15 years of age with de …

Background The objectives of this study were to investigate the mutation profiles of targeted
genes and copy number variations (CNVs) in normal cytogenetics (CN) pediatric acute …

The results of repeated karyotype analyses in the disease course in 43 children with de
novo acute myeloid leukemia (AML) are presented. Patients with clonal bone marrow …

Acute myelogenous leukemia (AML) is the second most common leukemia in children. The
diagnosis of AML requires the presence of blasts (> 30%) in the bone marrow in most cases …

Purpose Because cytogenetic data are essential for risk stratification of childhood acute
myeloid leukemia (AML), the impact of chromosomal aberrations is crucial. Patients and …