Human neuroblastoma SH-SY5Y cells are a widely-used human neuronal cell model in the
study of neurodegeneration. A recent study shows that, 1-methyl-4-phenylpyridine ion …

The transient receptor potential (TRP) channel TRPM2 is an ion channel that modulates cell
survival. We report here that full-length (TRPM2-L) and short (TRPM2-S) isoform expression …

The transient receptor potential (TRP) protein superfamily is a diverse group of voltage-
independent calcium-permeable cation channels expressed in mammalian cells. These …

Transient receptor potential melastatin 2 (TRPM2) ion channel has an essential function in
modulating cell survival following oxidant injury and is highly expressed in many cancers …

Melastatin-like transient receptor potential channel 2 (TRPM2) is an oxidant-sensitive and
cationic non-selective channel that is expressed in mammalian vascular endothelium. Here …

Oxidative stress resulting from the accumulation of high levels of reactive oxygen species is
a salient feature of, and a well-recognised pathological factor for, diverse pathologies. One …

A brief exposure to hydrogen peroxide (H2O2) induces severe deterioration of primary
cultured neurons in vitro. We have investigated a link between the H2O2-induced neuronal …

TRPM2 is a Ca 2+-permeable channel that is activated by oxidative stress and confers
susceptibility to cell death. Here, an isoform of TRPM2 was identified in normal human bone …

ABSTRACT Transient Receptor Potential Melastatin-like 7 (TRPM7), Transient Receptor
Potential Melastatin-like 8 (TRPM8) and Transient Receptor Potential Vanilloid-like 1 …

TRPM2 is a Ca2+-permeable channel activated by oxidative stress or TNF-α, and TRPM2
activation confers susceptibility to cell death. The mechanisms were examined here in …