Interactions of Cryptococcus with Dendritic Cells

KL Wozniak - Journal of Fungi, 2018 - mdpi.com
The fungal pathogens Cryptococcus neoformans and Cryptococcus gattii can cause life-
threatening infections in immune compromised and immune competent hosts. These …

Pulmonary Macrophage and Dendritic Cell Responses to Cryptococcus neoformans

BN Nelson, AN Hawkins, KL Wozniak - Frontiers in cellular and …, 2020 - frontiersin.org
The fungal pathogen Cryptococcus neoformans can cause life-threatening infections in
immune compromised individuals. This pathogen is typically acquired via inhalation, and …

T Cell and Dendritic Cell Immune Responses to Cryptococcus

KL Wozniak, SM Levitz - … : from human pathogen to model yeast, 2010 - Wiley Online Library
This chapter reviews current knowledge regarding the role of dendritic cells (DCs) and T
cells in the generation of protective immunity against Cryptococcus neoformans infections …

Dendritic Cells: Multifunctional Roles in Host Defenses to Cryptococcus Infections

KD Goughenour, AS Nair, J Xu, MA Olszewski… - Journal of Fungi, 2023 - mdpi.com
Fungal infections are an increasingly growing public health concern, and Cryptococcus is
one of the most problematic fungal organisms causing substantial mortality and morbidity …

Innate Pulmonary Phagocytes and Their Interactions with Pathogenic Cryptococcus Species

BN Conn, KL Wozniak - Journal of Fungi, 2023 - mdpi.com
Cryptococcus neoformans is an opportunistic fungal pathogen that causes over 180,000
annual deaths in HIV/AIDS patients. Innate phagocytes in the lungs, such as dendritic cells …

Innate Immune Responses to Cryptococcus

LJ Heung - Journal of fungi, 2017 - mdpi.com
Cryptococcus species are encapsulated fungi found in the environment that predominantly
cause disease in immunocompromised hosts after inhalation into the lungs. Even with …

Role of dendritic cell–pathogen interactions in the immune response to pulmonary cryptococcal infection

AJ Eastman, JJ Osterholzer, MA Olszewski - Future microbiology, 2015 - Taylor & Francis
This review discusses the unique contributions of dendritic cells (DCs) to T-cell priming and
the generation of effective host defenses against Cryptococcus neoformans (C. neo) …

Cryptococcus and Phagocytes: Complex Interactions that Influence Disease Outcome

CM Leopold Wager, CR Hole, KL Wozniak… - Frontiers in …, 2016 - frontiersin.org
Cryptococcus neoformans and C. gattii are fungal pathogens that cause life-threatening
disease. These fungi commonly enter their host via inhalation into the lungs where they …

Cryptococcus gattii is killed by dendritic cells, but evades adaptive immunity by failing to induce dendritic cell maturation

SM Huston, SS Li, D Stack… - The Journal of …, 2013 - journals.aai.org
During adaptive immunity to pathogens, dendritic cells (DCs) capture, kill, process, and
present microbial Ags to T cells. Ag presentation is accompanied by DC maturation driven …

Antifungal Activity of Plasmacytoid Dendritic Cells against Cryptococcus neoformans In Vitro Requires Expression of Dectin-3 (CLEC4D) and Reactive Oxygen …

CR Hole, CM Leopold Wager, AS Mendiola… - Infection and …, 2016 - Am Soc Microbiol
Conventional dendritic cells (cDCs) are critical for protection against pulmonary infection
with the opportunistic fungal pathogen Cryptococcus neoformans; however, the role of …