Oestrogen and the sexual dimorphism of pulmonary arterial hypertension: a translational challenge

JK Paulus, KE Roberts - European Respiratory Journal, 2013 - Eur Respiratory Soc
The striking female predominance in idiopathic and familial pulmonary arterial hypertension
(PAH) has been well documented since the publication of the National Institutes of Health …

Sex hormones across the menstrual cycle in pulmonary arterial hypertension: adding a new layer of complexity

ED Austin - Annals of the American Thoracic Society, 2021 - atsjournals.org
One of our most recent diagnoses is a 9-year-old male with heritable pulmonary arterial
hypertension (PAH) owing to a known rare variant (mutation) in a PAH-related gene. I ached …

The estrogen paradox in pulmonary arterial hypertension

S Sakao, N Tanabe, K Tatsumi - American Journal of …, 2010 - journals.physiology.org
Idiopathic pulmonary arterial hypertension (PAH) is a disabling condition characterized by
PA vasoconstriction and remodeling as well as in situ thrombosis and eventual right heart …

Gender, sex hormones and pulmonary hypertension

ED Austin, T Lahm, J West, SP Tofovic… - Pulmonary …, 2013 - journals.sagepub.com
Most subtypes of pulmonary arterial hypertension (PAH) are characterized by a greater
susceptibility to disease among females, although females with PAH appear to live longer …

Sex hormones

K Oshima, M Oka - Diagnosis and Treatment of Pulmonary Hypertension …, 2017 - Springer
Males and females are biologically distinct, and certain pathological conditions affect both
sexes differently. Obvious sex difference exists in pulmonary arterial hypertension (PAH) …

Gender, sex hormones, and pulmonary arterial hypertension

ED Austin - Advances in Pulmonary Hypertension, 2011 - meridian.allenpress.com
Pulmonary arterial hypertension (PAH) is a progressive disease characterized by pulmonary
vascular remodeling of the distal pulmonary vasculature, ultimately leading to destruction …

The role of sex in the pathophysiology of pulmonary hypertension

CK Docherty, KY Harvey, KM Mair, S Griffin… - Sex-Specific Analysis of …, 2018 - Springer
Pulmonary arterial hypertension (PAH) is a progressive disease characterised by increased
pulmonary vascular resistance and pulmonary artery remodelling as result of increased …

Pulmonary hypertension in women

ME Pugh, AR Hemnes - Expert review of cardiovascular therapy, 2010 - Taylor & Francis
Female predominance in pulmonary arterial hypertension (PAH) has been known for
several decades and recent interest in the effects of sex hormones on the development of …

Beyond oestrogens: towards a broader evaluation of the hormone profile in pulmonary arterial hypertension

JB Badlam, ED Austin - European Respiratory Journal, 2018 - Eur Respiratory Soc
Beyond oestrogens: towards a broader evaluation of the hormone profile in pulmonary arterial
hypertension | European Respiratory Society Skip to main content Main menu Home Current …

The estrogen puzzle in pulmonary arterial hypertension

R Paulin, ED Michelakis - Circulation, 2012 - Am Heart Assoc
The biology of pulmonary arterial hypertension (PAH) is full of mysteries, and one of its
longer-standing ones has also intrigued and inspired both scientists and artists throughout …