Netarsudil for the treatment of open-angle glaucoma and ocular hypertension: a literature review

LE Gonzalez, PM Boylan - Annals of Pharmacotherapy, 2021 - journals.sagepub.com
Objective: To evaluate netarsudil's role as first-line therapy for the treatment of open-angle
glaucoma (OAG) and ocular hypertension (OHT). Data Sources: A literature search utilizing …

Netarsudil: A new ophthalmic drug in the treatment of chronic primary open angle glaucoma and ocular hypertension

M Batra, S Gupta, AB Nair… - European Journal …, 2021 - journals.sagepub.com
Background: Vision impairment remains a major health problem worldwide. Elevated
intraocular pressure is a prime risk factor for blindness in the elderly. Netarsudil is a Rho …

A multicenter, open-label study of netarsudil for the reduction of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension in a real …

F Zaman, SC Gieser, GF Schwartz, C Swan… - Current Medical …, 2021 - Taylor & Francis
Objective Assess the real-world efficacy of netarsudil, either as monotherapy or concomitant
therapy, in patients with open-angle glaucoma (OAG) or ocular hypertension (OHT) …

[HTML][HTML] Netarsudil monotherapy as the initial treatment for open-angle glaucoma and ocular hypertension in Indian patients: A real-world evaluation of efficacy and …

MC Mathur, PV Ratnam, SJ Saikumar… - Indian Journal of …, 2023 - journals.lww.com
Purpose: Glaucoma is the second leading cause of blindness worldwide, affecting more
than 64 million people aged 40–80. The best way to manage primary open-angle glaucoma …

Fixed-dose combination of netarsudil and latanoprost in ocular hypertension and open-angle glaucoma: pooled efficacy/safety analysis of phase 3 MERCURY-1 and …

S Asrani, J Bacharach, E Holland, H McKee… - Advances in …, 2020 - Springer
Introduction New open-angle glaucoma (OAG) and ocular hypertension (OHT) therapies that
reduce treatment burden and improve outcomes relative to currently available agents are …

Phase 3 clinical trial comparing the safety and efficacy of netarsudil to ripasudil in patients with primary open-angle glaucoma or ocular hypertension: Japan Rho …

M Araie, K Sugiyama, K Aso, K Kanemoto, R Iwata… - Advances in …, 2023 - Springer
Introduction A clinical trial evaluated ocular hypotensive efficacy and safety of netarsudil
0.02% once daily (QD) relative to ripasudil 0.4% twice daily (BID). Methods This was a …

[HTML][HTML] Two phase 3 clinical trials comparing the safety and efficacy of netarsudil to timolol in patients with elevated intraocular pressure: rho kinase elevated IOP …

JB Serle, LJ Katz, E McLaurin, T Heah… - American journal of …, 2018 - Elsevier
Purpose To evaluate the efficacy and ocular and systemic safety of netarsudil 0.02%
ophthalmic solution, a rho-kinase inhibitor and norepinephrine transporter inhibitor, in …

Effectiveness and tolerability of netarsudil in combination with other ocular hypotensive agents

AJ Prager, M Tang, AL Pleet, LC Petito… - Ophthalmology …, 2021 - Elsevier
Purpose To evaluate the effectiveness of netarsudil in combination with other ocular
hypotensive agents in patients with open-angle glaucoma (OAG) or ocular hypertension …

The effectiveness and safety profile of netarsudil 0.02% in glaucoma treatment: real-world 6-month outcomes

EJ Shiuey, NA Mehran, M Ustaoglu, Q Zhang… - Graefe's Archive for …, 2022 - Springer
Purpose To evaluate the efficacy and safety profile of netarsudil 0.02% ophthalmic solution
in a tertiary glaucoma referral center. Methods This retrospective cohort study included …

Phase 2 randomized clinical study of netarsudil ophthalmic solution in Japanese patients with primary open-angle glaucoma or ocular hypertension

M Araie, K Sugiyama, K Aso, K Kanemoto… - Advances in …, 2021 - Springer
Introduction Netarsudil reduces intraocular pressure (IOP) by increasing aqueous outflow
through the trabecular meshwork (TM) pathway and decreasing episcleral venous pressure …