Blood‐spinal cord barrier after spinal cord injury: Relation to revascularization and wound healing

WD Whetstone, JYC Hsu, M Eisenberg… - Journal of …, 2003 - Wiley Online Library
Spinal cord injury produces prominent disruption of the blood‐spinal cord barrier. We have
defined the blood‐spinal cord barrier breakdown to the protein luciferase (61 kDa) in the …

A quantitative spatial analysis of the blood–spinal cord barrier: I. Permeability changes after experimental spinal contusion injury

PG Popovich, PJ Horner, BB Mullin, BT Stokes - Experimental neurology, 1996 - Elsevier
Blood–spinal cord barrier (BSB) permeability was measured using quantitative
autoradiography following contusion injury to the rat spinal cord. Permeability was assessed …

Characterization of vascular disruption and blood–spinal cord barrier permeability following traumatic spinal cord injury

SA Figley, R Khosravi, JM Legasto, YF Tseng… - Journal of …, 2014 - liebertpub.com
Significant vascular changes occur subsequent to spinal cord injury (SCI), which contribute
to progressive pathophysiology. In the present study, we used female Wistar rats (300–350 …

Spinal cord compression injury in guinea pigs: structural changes of endothelium and its perivascular cell associations after blood–brain barrier breakdown and repair

CB Jaeger, AR Blight - Experimental neurology, 1997 - Elsevier
This study examines morphological changes of the blood–brain barrier (BBB) after spinal
cord compression. The lowest thoracic segment (T13) of female guinea pigs was injured and …

Molecular and cellular mechanisms underlying the role of blood vessels in spinal cord injury and repair

M Oudega - Cell and tissue research, 2012 - Springer
Spinal cord injury causes immediate damage of nervous tissue accompanied by the loss of
motor and sensory function. The limited self-repair ability of damaged nervous tissue …

Blood flow and vascular permeability during motor dysfunction in a rabbit model of spinal cord ischemia.

TP Jacobs, O Kempski, D McKinley, AJ Dutka… - Stroke, 1992 - Am Heart Assoc
Delayed deterioration of neurological function after central nervous system ischemia is a
well-documented clinical problem. The purpose of our study was to elucidate the role of …

New vascular tissue rapidly replaces neural parenchyma and vessels destroyed by a contusion injury to the rat spinal cord

GTB Casella, A Marcillo, MB Bunge, PM Wood - Experimental neurology, 2002 - Elsevier
Blood vessels identified by laminin staining were studied in uninjured spinal cord and at 2,
4, 7, and 14 days following a moderate contusion (weight drop) injury. At 2 days after injury …

Vascular events after spinal cord injury: contribution to secondary pathogenesis

AEM Mautes, MR Weinzierl, F Donovan… - Physical …, 2000 - academic.oup.com
Traumatic spinal cord injury results in the disruption of neural and vascular structures
(primary injury) and is characterized by an evolution of secondary pathogenic events that …

Experimental spinal cord injury: Wallerian degeneration in the dorsal column is followed by revascularization, glial proliferation, and nerve regeneration

Z Zhang, L Guth - Experimental Neurology, 1997 - Elsevier
The presence of an adequate blood supply is a critical factor in recovery from traumatic
injuries. We have examined whether the revascularization of the injured tissues is as crucial …

Pathophysiology of blood-spinal cord barrier in traumatic injury and repair

HS Sharma - Current pharmaceutical design, 2005 - ingentaconnect.com
Blood-spinal cord barrier (BSCB) plays an important role in the regulation of the fluid
microenvironment of the spinal cord. Trauma to the spinal cord impairs the BSCB …