Cancer has become a major public health problem worldwide. Researches focus on the
new approaches for cancer treatments that involve the specific targets of the cancer disease …

The tremendous advances achieved in the understanding of cancer biology have delivered
unprecedented progress in molecularly targeted cancer therapy in the past decade. The fast …

The introduction of targeted therapy promised personalized and efficacious cancer
treatments. However, although some targeted therapies have undoubtedly improved …

Molecular targeted therapies are revolutionized therapeutics which interfere with specific
molecules to block cancer growth, progression, and metastasis. Many molecular targeted …

Targeted therapies can be defined as drugs developed against a specific target based on its
important biological function in cancer. In contrast, nontargeted therapies are drugs …

The advent of targeted therapy for treatment of human cancers has added significantly to our
armamentarium as we strive to prolong patient survival while minimizing toxicity. In cancers …

Cancer treatment faces many hurdles and resistance is one among them. Anti-cancer
treatment strategies are evolving due to innate and acquired resistance capacity, governed …

Resistance to chemotherapy agents is a major challenge infront of cancer patient treatment
and researchers. It is known that several factors, such as multidrug resistance proteins and …

Chemotherapy and molecularly targeted approaches represent two very different modes of
cancer treatment and each is associated with unique benefits and limitations. Both types of …

Drug resistance developed towards conventional therapy is one of the important reasons for
chemotherapy failure in cancer. The various underlying mechanism for drug resistance …