The initiation of transcription is the most important step for gene regulation in eubacteria. To
initiate transcription, RNA polymerase has to associate with a small protein, known as a σ …

Transcription is the fundamental process that enables the expression of genetic information.
DNA‐directed RNA polymerase (RNAP) uses one strand of the DNA duplex as template to …

Transcription is the first and most heavily regulated step in gene expression. Sigma (σ)
factors are general transcription factors that reversibly bind RNA polymerase (RNAP) and …

Transcription initiation is the crucial focal point of gene expression in prokaryotes. The key
players in this process, sigma factors (σs), associate with the catalytic core RNA polymerase …

Bacterial sigma (σ) factors confer gene specificity upon the RNA polymerase, the central
enzyme that catalyses gene transcription. The binding of the alternative σ factor σ54 confers …

Bacterial sigma (σ) factors are an essential component of RNA polymerase and determine
promoter selectivity. The substitution of one σ factor for another can redirect some or all of …

The initiation of transcription is a complex process involving many different steps. These
steps are all potential control points for regulating gene expression, and many have been …

In bacteria, σ factors are essential for the promoter DNA-binding specificity of RNA
polymerase. The σ factors themselves are regulated by anti-σ factors that bind and inhibit …

Bacterial σ factors play a key role in promoter recognition, making direct contact with
conserved promoter elements. Most σ factors belong to the σ70 family, named for the …

▪ Abstract Promoter recognition in eubacteria is carried out by the initiation factor sigma,
which binds RNA polymerase and initiates transcription. Cells have one housekeeping …