[HTML][HTML] Heterogeneity of colon cancer: from bench to bedside
MC Merlano, C Granetto, E Fea, V Ricci, O Garrone - ESMO open, 2017 - Elsevier
The large bowel shows biomolecular, anatomical and bacterial changes that proceed from
the proximal to the distal tract. These changes account for the different behaviour of colon …
the proximal to the distal tract. These changes account for the different behaviour of colon …
Molecular biomarkers according to primary tumor location in colorectal cancer: current standard and new insights
G De Renzi, G Gaballo, P Gazzaniga, C Nicolazzo - Oncology, 2021 - karger.com
According to the 2018 GLOBOCAN database, colorectal cancer is one of the most common
malignancies and leading causes of cancer-related death worldwide. During the last …
malignancies and leading causes of cancer-related death worldwide. During the last …
Tumor side as model of integrative molecular classification of colorectal cancer
R Dienstmann - Clinical Cancer Research, 2018 - AACR
It has long since been recognized that colorectal cancer is molecularly heterogeneous and
its clinical behavior differs if the primary tumor was located in the right or left side of the …
its clinical behavior differs if the primary tumor was located in the right or left side of the …
[HTML][HTML] Resolving the difference between left-sided and right-sided colorectal cancer by single-cell sequencing
W Guo, C Zhang, X Wang, D Dou, D Chen, J Li - JCI insight, 2022 - ncbi.nlm.nih.gov
Colorectal cancers (CRCs) exhibit differences in incidence, pathogenesis, molecular
pathways, and outcome depending on the location of the tumor. The transcriptomes of …
pathways, and outcome depending on the location of the tumor. The transcriptomes of …
A nationwide Danish cohort study challenging the categorisation into right-sided and left-sided colon cancer
P Jess, IO Hansen, M Gamborg, T Jess - BMJ open, 2013 - bmjopen.bmj.com
Objectives The categorisation of colon cancer (CC) into right-sided (RCC) and left-sided
(LCC) disease may not capture more subtle variances in aetiology and prognosis. In a …
(LCC) disease may not capture more subtle variances in aetiology and prognosis. In a …
[HTML][HTML] Laterality: right-sided and left-sided colon cancer
SK Baek - Annals of coloproctology, 2017 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) can be characterized by the location of the primary tumor being
within the colon [1]. Right-sided colon cancer (RCC) is derived from the embryologic midgut …
within the colon [1]. Right-sided colon cancer (RCC) is derived from the embryologic midgut …
[HTML][HTML] Location of colon cancer (right-sided versus left-sided) as a prognostic factor and a predictor of benefit from cetuximab in NCIC CO. 17
SY Brulé, DJ Jonker, CS Karapetis… - European journal of …, 2015 - Elsevier
Background Right-and left-sided colon cancers (RC, LC) differ with respect to biology,
pathology and epidemiology. Previous data suggest a mortality difference between RC and …
pathology and epidemiology. Previous data suggest a mortality difference between RC and …
Cancers of the colon and rectum: identical or fraternal twins?
TS Hong, JW Clark, KM Haigis - Cancer discovery, 2012 - AACR
Colorectal cancer represents a major cause of cancer morbidity and mortality, with
approximately 1.2 million cases and 600,000 deaths worldwide each year. Because of the …
approximately 1.2 million cases and 600,000 deaths worldwide each year. Because of the …
[HTML][HTML] Prognostic factors and survival disparities in right-sided versus left-sided colon cancer
Right-sided colon cancer (RCC) and left-sided colon cancer (LCC) differ in features and
outcomes because of variations in embryology, epidemiology, pathology, and prognosis …
outcomes because of variations in embryology, epidemiology, pathology, and prognosis …
Combination gut microbiota modulation and chemotherapy for orthotopic colorectal cancer therapy
ZX Chen, JL Li, P Pan, P Bao, X Zeng, XZ Zhang - Nano Today, 2021 - Elsevier
Gut microbiota is closely related to the tumorigenesis and progression of colorectal cancer
(CRC), especially Fusobacterium nucleatum (Fn) could promote colorectal tumor growth and …
(CRC), especially Fusobacterium nucleatum (Fn) could promote colorectal tumor growth and …