This study aims to determine differences in the on-and off-tumor microbiota between patients
with right-and left-sided colorectal cancer. Microbiome profiling of tumor and tumor-adjacent …

Background Prior reports have demonstrated inferior outcomes for patients with right-sided
colorectal cancer (CRC) compared to patients with left-sided disease, as well as differences …

Purpose: Colorectal carcinomas that arise proximal (right) or distal (left) to the splenic flexure
exhibit different clinical and biological characteristics. Although various hypotheses have …

Background While mechanisms contributing to the progression and metastasis of colorectal
cancer (CRC) are well studied, cancer stage-specific mechanisms have been less …

Opinion statement Colorectal cancer does not represent a single anatomic entity and side of
origin has a key impact on prognosis and response to different systemic therapies …

Background Right-sided colon cancers (RCC) and left-sided colon cancers (LCC) are of
different embryological origins, and various differences exist between them. However, the …

Colorectal cancer is the third most common cancer worldwide with a high mortality rate at
the advanced stages. However, colorectal cancer is not a single type of tumor; its …

Purpose: Response to standard oncologic treatment is limited in colorectal cancer. The gene
expression–based consensus molecular subtypes (CMS) provide a new paradigm for …

Background: There has been an increasing interest in the role of tumour location in the
treatment and prognosis of patients with colorectal cancer (CRC), specifically in the adjuvant …

Patients with colorectal cancer (CRC) often exhibit changes in body composition (BC) which
are associated with poorer clinical outcomes. Many studies group colon and rectal cancers …