[HTML][HTML] Cartilage Decellularized Matrix Hydrogel Loaded with Protocatechualdehyde for Targeted Epiphycan Treatment of Osteoarthritis

J Huang, Z Bu, W Liu, Z Zhou, J Hu, J Yu, H Wang… - Materials Today Bio, 2024 - Elsevier
Osteoarthritis (OA) is a prevalent chronic disease, characterized by chronic inflammation
and cartilage degradation. This study aims to deepen the understanding of OA's …

Epigallocatechin-3-O-gallate promotes extracellular matrix and inhibits inflammation in IL-1β stimulated chondrocytes by the PTEN/miRNA-29b pathway

D Yang, G Cao, X Ba, H Jiang - Pharmaceutical Biology, 2022 - Taylor & Francis
Abstract Context Epigallocatechin-3-O-gallate (EGCG) exhibits anti-arthritic activity. MiR-29b-
3p provokes chondrocyte apoptosis and promotes the initiation and development of …

Injectable PNIPAM/Hyaluronic acid hydrogels containing multipurpose modified particles for cartilage tissue engineering: Synthesis, characterization, drug release …

Z Atoufi, SK Kamrava, SM Davachi… - International journal of …, 2019 - Elsevier
Novel injectable thermosensitive PNIPAM/hyaluronic acid hydrogels containing various
amounts of chitosan-g-acrylic acid coated PLGA (ACH-PLGA) micro/nanoparticles were …

Fabrication of injectable high strength hydrogel based on 4-arm star PEG for cartilage tissue engineering

J Wang, F Zhang, WP Tsang, C Wan, C Wu - Biomaterials, 2017 - Elsevier
Hydrogels prepared from poly (ethylene glycol)(PEG) are widely applied in tissue
engineering, especially those derived from a combination of functional multi-arm star PEG …

A Novel EphA4 Signaling‐Based Therapeutic Strategy for Osteoarthritis in Mice

VM Stiffel, CH Rundle, MHC Sheng… - Journal of Bone and …, 2020 - academic.oup.com
This study took advantage of the recent discovery that the EphA4 signaling has anti‐
catabolic effects on osteoclasts/macrophages/synoviocytes but pro‐anabolic effects on …

Injectable anti-inflammatory hyaluronic acid hydrogel for osteoarthritic cartilage repair

Y Jin, RH Koh, SH Kim, KM Kim, GK Park… - Materials Science and …, 2020 - Elsevier
Osteoarthritis (OA) is one of the most common cartilage disorder that results from breakdown
of joint cartilage and underlying bone tissues. Once OA is induced in the joint, subsequent …

Tissue engineering: development of a cellularly degradable PEG hydrogel to promote articular cartilage extracellular matrix deposition (Adv. Healthcare Mater. 5/2015 …

BV Sridhar, JL Brock, JS Silver… - Advanced …, 2015 - Wiley Online Library
A cellularly degradable hydrogel based on peptide and protein functionalized PEG is
designed on page 702 by MA Randolph, KS Anseth, and co-workers to allow local, cell …

Hyaluronic Acid Viscosupplement Modulates Inflammatory Mediators in Chondrocyte and Macrophage Coculture via MAPK and NF-κB Signaling Pathways

SS Kuppa, JY Kang, HY Yang, SC Lee… - ACS …, 2024 - ACS Publications
Osteoarthritis (OA) is a chronic musculoskeletal disorder characterized by cartilage
degeneration and synovial inflammation. Paracrine interactions between chondrocytes and …

[HTML][HTML] A multifunctional nanogel encapsulating layered double hydroxide for enhanced osteoarthritis treatment via protection of chondrocytes and ECM

C Liu, Y Sun, D Li, F Wang, H Wang, S An, S Sun - Materials Today Bio, 2024 - Elsevier
Osteoarthritis (OA) is characterized by progressive and irreversible damage to the articular
cartilage and a consecutive inflammatory response. However, the majority of clinical drugs …

Injectable polyethylene glycol-laponite composite hydrogels as articular cartilage scaffolds with superior mechanical and rheological properties

A Nojoomi, E Tamjid, A Simchi… - … Journal of Polymeric …, 2017 - Taylor & Francis
In this study, injectable PEG-based hydrogels containing Laponite particles with mechanical
and structural properties close to the natural articular cartilage are introduced. The …