[HTML][HTML] Cartilage Decellularized Matrix Hydrogel Loaded with Protocatechualdehyde for Targeted Epiphycan Treatment of Osteoarthritis
J Huang, Z Bu, W Liu, Z Zhou, J Hu, J Yu, H Wang… - Materials Today Bio, 2024 - Elsevier
Osteoarthritis (OA) is a prevalent chronic disease, characterized by chronic inflammation
and cartilage degradation. This study aims to deepen the understanding of OA's …
and cartilage degradation. This study aims to deepen the understanding of OA's …
Epigallocatechin-3-O-gallate promotes extracellular matrix and inhibits inflammation in IL-1β stimulated chondrocytes by the PTEN/miRNA-29b pathway
D Yang, G Cao, X Ba, H Jiang - Pharmaceutical Biology, 2022 - Taylor & Francis
Abstract Context Epigallocatechin-3-O-gallate (EGCG) exhibits anti-arthritic activity. MiR-29b-
3p provokes chondrocyte apoptosis and promotes the initiation and development of …
3p provokes chondrocyte apoptosis and promotes the initiation and development of …
Injectable PNIPAM/Hyaluronic acid hydrogels containing multipurpose modified particles for cartilage tissue engineering: Synthesis, characterization, drug release …
Novel injectable thermosensitive PNIPAM/hyaluronic acid hydrogels containing various
amounts of chitosan-g-acrylic acid coated PLGA (ACH-PLGA) micro/nanoparticles were …
amounts of chitosan-g-acrylic acid coated PLGA (ACH-PLGA) micro/nanoparticles were …
Fabrication of injectable high strength hydrogel based on 4-arm star PEG for cartilage tissue engineering
J Wang, F Zhang, WP Tsang, C Wan, C Wu - Biomaterials, 2017 - Elsevier
Hydrogels prepared from poly (ethylene glycol)(PEG) are widely applied in tissue
engineering, especially those derived from a combination of functional multi-arm star PEG …
engineering, especially those derived from a combination of functional multi-arm star PEG …
A Novel EphA4 Signaling‐Based Therapeutic Strategy for Osteoarthritis in Mice
VM Stiffel, CH Rundle, MHC Sheng… - Journal of Bone and …, 2020 - academic.oup.com
This study took advantage of the recent discovery that the EphA4 signaling has anti‐
catabolic effects on osteoclasts/macrophages/synoviocytes but pro‐anabolic effects on …
catabolic effects on osteoclasts/macrophages/synoviocytes but pro‐anabolic effects on …
Injectable anti-inflammatory hyaluronic acid hydrogel for osteoarthritic cartilage repair
Osteoarthritis (OA) is one of the most common cartilage disorder that results from breakdown
of joint cartilage and underlying bone tissues. Once OA is induced in the joint, subsequent …
of joint cartilage and underlying bone tissues. Once OA is induced in the joint, subsequent …
Tissue engineering: development of a cellularly degradable PEG hydrogel to promote articular cartilage extracellular matrix deposition (Adv. Healthcare Mater. 5/2015 …
BV Sridhar, JL Brock, JS Silver… - Advanced …, 2015 - Wiley Online Library
A cellularly degradable hydrogel based on peptide and protein functionalized PEG is
designed on page 702 by MA Randolph, KS Anseth, and co-workers to allow local, cell …
designed on page 702 by MA Randolph, KS Anseth, and co-workers to allow local, cell …
Hyaluronic Acid Viscosupplement Modulates Inflammatory Mediators in Chondrocyte and Macrophage Coculture via MAPK and NF-κB Signaling Pathways
SS Kuppa, JY Kang, HY Yang, SC Lee… - ACS …, 2024 - ACS Publications
Osteoarthritis (OA) is a chronic musculoskeletal disorder characterized by cartilage
degeneration and synovial inflammation. Paracrine interactions between chondrocytes and …
degeneration and synovial inflammation. Paracrine interactions between chondrocytes and …
[HTML][HTML] A multifunctional nanogel encapsulating layered double hydroxide for enhanced osteoarthritis treatment via protection of chondrocytes and ECM
C Liu, Y Sun, D Li, F Wang, H Wang, S An, S Sun - Materials Today Bio, 2024 - Elsevier
Osteoarthritis (OA) is characterized by progressive and irreversible damage to the articular
cartilage and a consecutive inflammatory response. However, the majority of clinical drugs …
cartilage and a consecutive inflammatory response. However, the majority of clinical drugs …
Injectable polyethylene glycol-laponite composite hydrogels as articular cartilage scaffolds with superior mechanical and rheological properties
In this study, injectable PEG-based hydrogels containing Laponite particles with mechanical
and structural properties close to the natural articular cartilage are introduced. The …
and structural properties close to the natural articular cartilage are introduced. The …
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