The obese adipose tissue microenvironment in cancer development and progression

DF Quail, AJ Dannenberg - Nature Reviews Endocrinology, 2019 - nature.com
Obesity is associated with both increased cancer incidence and progression in multiple
tumour types, and is estimated to contribute to up to 20% of cancer-related deaths. These …

[HTML][HTML] Association between obesity-related adipokines and colorectal cancer: a case-control study and meta-analysis

RK Joshi, WJ Kim, SA Lee - World Journal of Gastroenterology …, 2014 - ncbi.nlm.nih.gov
AIM: To examine the association between obesity-related adipokines (adiponectin, leptin,
resistin, interleukin-6 (IL-6), and tumor necrosis factor-α (TNF-α) and colorectal cancer …

[HTML][HTML] Obesity and cancer: a current overview of epidemiology, pathogenesis, outcomes, and management

S Pati, W Irfan, A Jameel, S Ahmed, RK Shahid - Cancers, 2023 - mdpi.com
Simple Summary Obesity has been linked to several common cancers including breast,
colorectal, esophageal, kidney, gallbladder, uterine, pancreatic, and liver cancer. Obesity …

Leptin and gastro‐intestinal malignancies

JM Howard, GP Pidgeon, JV Reynolds - Obesity Reviews, 2010 - Wiley Online Library
Obesity is a well‐established risk factor for the development and mortality from several
cancers, including adenocarcinoma of the oesophagus, oesophago‐gastric junction and …

The balance between leptin and adiponectin in the control of carcinogenesis–focus on mammary tumorigenesis

ME Grossmann, MP Cleary - Biochimie, 2012 - Elsevier
A number of studies indicate that a growing list of cancers may be influenced by obesity. In
obese individuals these cancers can be more frequent and more aggressive resulting in …

Adiposity, type 2 diabetes and the metabolic syndrome in breast cancer

L Vona‐Davis, M Howard‐McNatt, DP Rose - Obesity Reviews, 2007 - Wiley Online Library
Upper body obesity and the related metabolic disorder type 2 diabetes have been identified
as risk factors for breast cancer, and associated with late‐stage disease and a poor …

Obesity and Inflammation Lead to Insulin Resistance and Cancer—A Systematic Review

M Shafiul Hossen, M Abdul Barek… - Obesity: Clinical, Surgical …, 2024 - Springer
Adipose tissue mass is increased in obese people due to the increasing size and number of
adipocytes. It significantly changes the adipocytokines and inflammatory mediators secretion …