Chondroitin sulfate proteoglycans in neural development and regeneration

WL Gu, PH Lu - Sheng li ke xue jin Zhan [Progress in Physiology], 2007 - europepmc.org
Chondroitin sulfate proteoglycans (CSPGs) are major components of extracellular matrix in
the central nervous system (CNS), and play important roles in the development and …

Comparative analysis of the expression of chondroitin sulfate subtypes and their inhibitory effect on axonal growth in the embryonic, adult, and injured rat brains

MH Kim, SR Park, BH Choi - Tissue Engineering and Regenerative …, 2021 - Springer
Background: Chondroitin sulfate glycosaminoglycans (CS-GAGs) are the primary inhibitory
GAGs for neuronal growth after central nervous system (CNS) injury. However, the inhibitory …

Chondroitin sulfate proteoglycans: Key modulators in the developing and pathologic central nervous system

SM Dyck, S Karimi-Abdolrezaee - Experimental neurology, 2015 - Elsevier
Abstract Chondroitin Sulfate Proteoglycans (CSPGs) are a major component of the
extracellular matrix in the central nervous system (CNS) and play critical role in the …

Inhibiting glycosaminoglycan chain polymerization decreases the inhibitory activity of astrocyte-derived chondroitin sulfate proteoglycans

TL Laabs, H Wang, Y Katagiri, T McCann… - Journal of …, 2007 - Soc Neuroscience
Chondroitin sulfate proteoglycans (CSPGs) are upregulated in the CNS after injury and
participate in the inhibition of axon regeneration mainly through their glycosaminoglycan …

Chondroitin sulfates in axon regeneration and plasticity

JCF Kwok, CL Tan, D Wang, J Heller… - Trends in Glycoscience …, 2011 - jlc.jst.go.jp
Chondroitin sulfate proteoglycans (CSPGs) are large extracellular matrix molecules which
are highly upregulated in the glial scar after injury to the nervous system. They are mostly …

Targeting inhibitory chondroitin sulphate proteoglycans to promote plasticity after injury

JCF Kwok, JP Heller, RR Zhao, JW Fawcett - Axon growth and …, 2014 - Springer
Chondroitin sulphate proteoglycans (CSPGs) are one of the major families of inhibitory
extracellular matrix molecules in the central nervous system. The expression of various …

Chondroitin sulfate proteoglycans: key modulators of neuronal plasticity, long-term memory, neurodegenerative, and psychiatric disorders

X Yang - Reviews in the Neurosciences, 2020 - degruyter.com
The chondroitin sulfate proteoglycans (CSPGs) are large groups of heterogenous
proteoglycans that are mainly expressed by reactive astrocytes in the central nervous …

Mechanisms for modulation of neural plasticity and axon regeneration by chondroitin sulphate

S Miyata, H Kitagawa - The journal of biochemistry, 2015 - academic.oup.com
Chondroitin sulphate proteoglycans (CSPGs), consisting of core proteins linked to one or
more chondroitin sulphate (CS) chains, are major extracellular matrix (ECM) components of …

Structural variation of chondroitin sulfate and its roles in the central nervous system

N Maeda - Central Nervous System Agents in Medicinal …, 2010 - ingentaconnect.com
Chondroitin sulfate is popular in the field of neuroscience, because the treatment of nervous
tissues with chondroitinase ABC, which degrades chondroitin sulfate up to unsaturated …

Chondroitin sulfate glycosaminoglycans for CNS homeostasis-implications for material design

L Karumbaiah, T Saxena, M Betancur… - Current medicinal …, 2014 - ingentaconnect.com
Chondroitin sulfate proteoglycans (CSPGs) are complex biomolecules that are known to
facilitate patterning of axonal direction and cell migration during the early growth and …