Immunopathogenesis of inflammatory bowel disease and mechanisms of biological therapies

B Ahluwalia, L Moraes, MK Magnusson… - Scandinavian journal of …, 2018 - Taylor & Francis
Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the gastrointestinal
tract with a multifactorial pathophysiology. Full comprehension of IBD pathology is still out of …

Pathophysiology of inflammatory bowel diseases

JT Chang - New England Journal of Medicine, 2020 - Mass Medical Soc
Pathophysiology of Inflammatory Bowel Diseases Research on IBDs has identified disrupted
immune responses in the gastrointestinal mucosa and putative disruptions in the gut …

Etiopathogenesis of inflammatory bowel disease: today and tomorrow

HSP de Souza - Current opinion in gastroenterology, 2017 - journals.lww.com
The continuing identification of several epigenetic, transcriptomic, proteomic, and
metabolomic alterations in patients with IBD reflects the complex nature of the disease and …

Pathophysiology of inflammatory bowel disease: innate immune system

A Saez, B Herrero-Fernandez, R Gomez-Bris… - International journal of …, 2023 - mdpi.com
Inflammatory bowel disease (IBD), comprising Crohn's disease (CD) and ulcerative colitis
(UC), is a heterogeneous state of chronic intestinal inflammation with no exact known cause …

Association among genetic predisposition, gut microbiota, and host immune response in the etiopathogenesis of inflammatory bowel disease

PJ Basso, MTC Fonseca, G Bonfá… - Brazilian Journal of …, 2014 - SciELO Brasil
Inflammatory bowel disease (IBD), which includes Crohn's disease (CD) and ulcerative
colitis (UC), is a chronic disorder that affects thousands of people around the world. These …

[HTML][HTML] Etiopathogenesis of inflammatory bowel diseases

S Danese, C Fiocchi - World journal of gastroenterology: WJG, 2006 - ncbi.nlm.nih.gov
Theories explaining the etiopathogenesis of inflammatory bowel disease (IBD) have been
proposed ever since Crohn's disease (CD) and ulcerative colitis (UC) were recognized as …

[HTML][HTML] Pathogenesis of inflammatory bowel disease and recent advances in biologic therapies

DH Kim, JH Cheon - Immune network, 2017 - ncbi.nlm.nih.gov
Inflammatory bowel disease (IBD) is a chronic intestinal inflammatory disorder with an
unknown etiology. IBD is composed of two different disease entities: Crohn's disease (CD) …

Inflammatory bowel disease: progress and current concepts of etiopathogenesis

F Scaldaferri, C Fiocchi - Journal of digestive diseases, 2007 - Wiley Online Library
Over the past few years, none of the numerous conditions that are grouped under the broad
designation of 'chronic inflammatory or autoimmune disorders' has undergone as much …

New insights into inflammatory bowel disease pathophysiology: paving the way for novel therapeutic targets

T Stefanelli, A Malesci, A Repici, S Vetrano… - Current Drug …, 2008 - ingentaconnect.com
The etiopathogenesis of Crohn's disease (CD) and ulcerative Colitis (UC), the two major
forms of inflammatory bowel disease (IBD), is still unknown. Although the exact cause and …

Inflammatory bowel disease: etiology, pathogenesis and current therapy

JK Ko, KK Auyeung - Current pharmaceutical design, 2014 - ingentaconnect.com
Ulcerative colitis (UC) and Crohn's disease (CD) constitute the two major groups of
idiopathic disorders in inflammatory bowel disease (IBD). Environmental factors, genetic …