Environmental triggers for IBD

A O'Toole, J Korzenik - Current gastroenterology reports, 2014 - Springer
The fundamental elucidation of how environmental influences provoke the initiation of
disease as well as flares of inflammatory bowel disease (IBD) remains incomplete. The …

Immunology of inflammatory bowel disease: molecular mechanisms and therapeutics

Q Lu, M Yang, Y Liang, J Xu, H Xu, Y Nie… - Journal of …, 2022 - Taylor & Francis
As a main digestive organ and an important immune organ, the intestine plays a vital role in
resisting the invasion of potential pathogens into the body. Intestinal immune dysfunction …

The role of bacteria in the inflammatory bowel disease development: a narrative review

T Azimi, MJ Nasiri, AS Chirani, R Pouriran, H Dabiri - Apmis, 2018 - Wiley Online Library
Inflammatory bowel disease (IBD) is a general term used for the ulcerative colitis (UC) and
Crohn's disease (CD); in addition, IBD principally refers to a chronic disease of the …

Natural history and complications of IBD

MH Vatn - Current gastroenterology reports, 2009 - Springer
Inflammatory bowel diseases (IBD), mainly ulcerative colitis and Crohn's disease, are
chronic, heterogenic, lifelong illnesses with young age of onset and a great potential for …

Challenges in IBD research: preclinical human IBD mechanisms

TT Pizarro, TS Stappenbeck, F Rieder… - Inflammatory bowel …, 2019 - academic.oup.com
Preclinical human IBD mechanisms is part of five focus areas of the Challenges in IBD
research document, which also include environmental triggers, novel technologies …

Inflammatory bowel disease: complexity and variability need integration

C Fiocchi - Frontiers in Medicine, 2018 - frontiersin.org
In the last century, humanity has being increasingly affected by a large number of chronic
conditions that fall into two major categories: neoplastic and inflammatory diseases. Unlike …

[HTML][HTML] Influence of environmental factors in the development of inflammatory bowel diseases

E Legaki, M Gazouli - World journal of gastrointestinal …, 2016 - ncbi.nlm.nih.gov
Idiopathic inflammatory bowel diseases (IBD), Crohn's disease (CD) and ulcerative colitis
(UC), are multifactorial diseases that are manifested after disruption of a genetic …

Microbiota and mucosal defense in IBD: an update

EF Stange, BO Schroeder - Expert review of gastroenterology & …, 2019 - Taylor & Francis
Introduction: Inflammatory bowel diseases (IBD) are on the rise worldwide. This review
covers the current concepts of the etiology of Crohn´ s disease and ulcerative colitis by …

An overview of the innate and adaptive immune system in inflammatory bowel disease

MC Choy, K Visvanathan… - Inflammatory bowel …, 2017 - academic.oup.com
Inflammatory bowel diseases (IBDs) are thought to develop as a result of complex
interactions between host genetics, the immune system and the environment including the …

Challenges in IBD research: precision medicine

LA Denson, M Curran, DPB McGovern… - Inflammatory bowel …, 2019 - academic.oup.com
Precision medicine is part of five focus areas of the Challenges in IBD research document,
which also includes preclinical human IBD mechanisms, environmental triggers, novel …