[HTML][HTML] Clinical applications of genomic alterations in ATLL: predictive markers and therapeutic targets

N Yoshida, H Miyoshi, K Ohshima - Cancers, 2021 - mdpi.com
Simple Summary In this review paper, we aim to summarize recent findings of genomic
alterations found in adult T-cell leukemia/lymphoma (ATLL), which is an incurable disease …

[HTML][HTML] Genetic alterations in adult T-cell leukemia/lymphoma: novel discoveries with clinical and biological significance

S Sakihama, K Karube - Cancers, 2022 - mdpi.com
Simple Summary In recent years, many researchers have devoted their efforts to clarifying
the genomic aberrations of adult T-cell leukemia/lymphoma (ATLL), and the overview of …

Genomic landscape of young ATLL patients identifies frequent targetable CD28 fusions

N Yoshida, K Shigemori, N Donaldson… - Blood, The Journal …, 2020 - ashpublications.org
Adult T-cell leukemia/lymphoma (ATLL) in Japan presents at a median age of 70 years and
only 5% of patients are< 50 years of age. We conducted RNA and targeted DNA sequencing …

The genomic landscape of adult T cell leukemia/lymphoma

C Vicente, J Cools - Nature genetics, 2015 - nature.com
Adult T cell leukemia/lymphoma (ATL) is a neoplasm linked to human T-lymphotropic virus
type-1 (HTLV-1) infection and is refractory to current combination chemotherapy. A large …

[HTML][HTML] Clonal selection and evolution of HTLV-1-infected cells driven by genetic and epigenetic alteration

M Yamagishi, Y Suzuki, T Watanabe, K Uchimaru - Viruses, 2022 - mdpi.com
T cells infected with human T-cell leukemia virus type 1 (HTLV-1) acquire various
abnormalities during a long latent period and transform into highly malignant adult T-cell …

[HTML][HTML] Potential miRNA-gene interactions determining progression of various ATLL cancer subtypes after infection by HTLV-1 oncovirus

MZ Ghobadi, E Afsaneh, R Emamzadeh… - BMC Medical …, 2023 - Springer
Abstract Background Adult T-cell Leukemia/Lymphoma (ATLL) is a rapidly progressing type
of T-cell non-Hodgkin lymphoma that is developed after the infection by human T-cell …

Genetic profile of adult T‐cell leukemia/lymphoma in Okinawa: Association with prognosis, ethnicity, and HTLV‐1 strains

S Sakihama, K Morichika, R Saito, M Miyara… - Cancer …, 2021 - Wiley Online Library
Genetic alterations in adult T‐cell leukemia/lymphoma (ATLL), a T‐cell malignancy
associated with HTLV‐1, and their clinical impacts, especially from the perspective of viral …

Signaling factors potentially associated to the pathogenesis of adult T-cell leukemia/lymphoma: a network-analysis and novel findings assessment

SH Mozhgani, MZ Ghobadi, M Norouzi, H Rahimi… - Virus research, 2022 - Elsevier
Adult T-cell leukemia/lymphoma (ATLL) is a human T-cell leukemia virus (HTLV) type 1-
associated disease of TCD4+ cell transformation. Despite extensive studies on ATLL …

Comprehensive genomic analysis identifying heterogeneity in peripheral T‐cell lymphoma

N Yoshida, K Yamada, K Ohshima - Cancer Science, 2021 - Wiley Online Library
Peripheral T‐cell lymphoma (PTCL) is a heterogeneous entity generally with a poor
prognosis. Recent genomic analyses have characterized genomic alterations and described …

Whole-genome landscape of adult T-cell leukemia/lymphoma

Y Kogure, T Kameda, J Koya… - Blood, The Journal …, 2022 - ashpublications.org
Adult T-cell leukemia/lymphoma (ATL) is an aggressive neoplasm immunophenotypically
resembling regulatory T cells, associated with human T-cell leukemia virus type-1. Here, we …