Gut-microbiota-derived metabolites maintain gut and systemic immune homeostasis

J Wang, N Zhu, X Su, Y Gao, R Yang - Cells, 2023 - mdpi.com
The gut microbiota, including bacteria, archaea, fungi, viruses and phages, inhabits the
gastrointestinal tract. This commensal microbiota can contribute to the regulation of host …

[HTML][HTML] The gut microbiota at the service of immunometabolism

C Michaudel, H Sokol - Cell metabolism, 2020 - cell.com
The gut microbiota is implicated in immune system functions. Regulation of the metabolic
processes occurring in immune cells is crucial for the maintenance of homeostasis and …

Gut microbiota-derived metabolites in the regulation of host immune responses and immune-related inflammatory diseases

W Yang, Y Cong - Cellular & molecular immunology, 2021 - nature.com
The gut microbiota has a critical role in the maintenance of immune homeostasis. Alterations
in the intestinal microbiota and gut microbiota-derived metabolites have been recognized in …

Microbiome, metabolites and host immunity

M Levy, E Blacher, E Elinav - Current opinion in microbiology, 2017 - Elsevier
Highlights•The gut encompasses thousands of small metabolites, collectively termed the
metabolome.•The metabolome is contributed by diet, the host, and its microbiome.•Multiple …

Bridging intestinal immunity and gut microbiota by metabolites

G Wang, S Huang, Y Wang, S Cai, H Yu, H Liu… - Cellular and Molecular …, 2019 - Springer
The gastrointestinal tract is the site of nutrient digestion and absorption and is also colonized
by diverse, highly mutualistic microbes. The intestinal microbiota has diverse effects on the …

Diet and gut microbiota in health and disease

TCD Shen - Intestinal microbiome: functional aspects in health and …, 2017 - karger.com
Gut microbiota plays an important role in host health maintenance and disease
pathogenesis. The development of a stable and diverse gut microbiota is essential to …

Microbiota metabolite regulation of host immune homeostasis: a mechanistic missing link

S Steinmeyer, K Lee, A Jayaraman… - Current allergy and asthma …, 2015 - Springer
Metazoans predominantly co-exist with symbiotic microorganisms called the microbiota.
Metagenomic surveys of the microbiota reveal a diverse ecosystem of microbes particularly …

[HTML][HTML] Metabolite interactions between host and microbiota during health and disease: Which feeds the other?

Y Zhang, R Chen, DD Zhang, S Qi, Y Liu - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Metabolites produced by the host and microbiota play a crucial role in how human bodies
develop and remain healthy. Most of these metabolites are produced by microbiota and …

Microbial metabolites determine host health and the status of some diseases

P Sittipo, J Shim, YK Lee - International journal of molecular sciences, 2019 - mdpi.com
The gastrointestinal (GI) tract is a highly complex organ composed of the intestinal
epithelium layer, intestinal microbiota, and local immune system. Intestinal microbiota …

Messengers from the gut: gut microbiota-derived metabolites on host regulation

C Li, Y Liang, Y Qiao - Frontiers in Microbiology, 2022 - frontiersin.org
The human gut is the natural habitat for trillions of microorganisms, known as the gut
microbiota, which play indispensable roles in maintaining host health. Defining the …