With the introduction of cyclosporin A in the early 1980s, heart transplantation was
transformed from an experimental procedure into a successful therapeutic option for patients …

There has been significant progress in the field of heart transplantation over the last 45
years. The 1-yr survival rates following heart transplantation have improved from 30% in the …

Little more than 30 years after the first human operation, heart transplantation continues to
be the gold standard treatment for heart failure disease. During these years, surgical …

Summary QUESTIONS UNDER STUDY: The field of heart transplantation has seen
substantial progress in the last 40 years. The breakthroughs in long-term survival were …

The prevalence of heart failure continues to rise due to the aging population and longer
survival of people with conditions that lead to heart failure, eg, hypertension, diabetes, and …

ABSTRACT In 1967, Christian Barnard performed the first successful human-to-human heart
transplant. Following this triumph, the ensuing decade saw a waning interest in heart …

Cardiac transplantation, first introduced 30 years ago, has become a widely used and
increasingly important procedure for treatment of truly end-stage heart disease. Current use …

Although the world of advanced heart failure has intensely focused its spotlight on
mechanical circulatory support, the field of heart transplantation has continued to evolve. We …

The first human heart transplantation was performed by Christian Barnard in 1967. While the
technical aspect had been worked out, allograft rejection was a major limitation in the early …

▪ Abstract Heart transplantation has evolved over the past 30 years into a mainstay of
therapy for heart failure patients. As the surgical technique and basic immunology were …