Besides the Watson–Crick double helix, DNA can, if strict sequence requirements are met,
adopt structures consisting of three or four strands, triplexes and quadruplexes. G …

Guanine-rich oligonucleotides are able to self-associate to form G-quadruplexes, a higher-
order DNA structure, in the presence of certain cations (typically Na+ and K+ ions).[1–3] G …

We report herein the successful design of the first molecule that induces the folding of the
parallel human telomeric G-quadruplex from single-stranded DNA in the absence of added …

Guanine-and cytosine-rich sequences may fold into tetraplex structures called G-
quadruplexes (G4) and i-motifs under certain conditions.[1–3] In 2002, we defined the …

Guanine-rich DNA sequences are known to form highly ordered structures called G
quadruplexes.[1] These structures play an important role in many relevant biological …

Sequence inversion in G‐rich DNA from 5′→ 3′ to 3′→ 5′ exerts a substantial effect on
the number of structures formed, while the type of G‐quadruplex fold is in fact determined by …

Guanine-rich (G-rich) sequences of DNA form G-quadruplexes, a non-canonical structure
stabilized by stacked G-quartets consisting of four guanine bases that interact through …

Tandem-repetitive guanine-rich DNA can fold into a fourstranded structure termed a G-
quadruplex through Hoogsteen hydrogen bonding.[1] Great interest in this structure arose …

Since the seminal report in 1997 on small molecules designed to interact with G-quadruplex
DNA,[1] an impressive number of candidates have been evaluated for binding to this …

Four-stranded DNA structures formed by guanine-rich sequences are known as G-
quadruplexes. They have received much interest over the last decade owing to their …