Chronic infection with hepatitis C virus (HCV) causes a quantitative and functional alteration
in innate and adaptative immunity. In the present work, we determined by flow-cytometry the …

Our purpose was to determine in HCV-infected patients whether T-lymphocyte sub-
populations were modified before and during interferon-alpha and ribavirin treatment, and …

We analyzed the relationship between virological response and baseline immune factors in
17 patients chronically infected with hepatitis C virus (HCV) who received interferon-α …

Background & Aims: The role of virus-specific T-helper lymphocyte reactivity in determining
the therapeutic response in chronic hepatitis C virus (HCV) infection is not fully understood …

Hepatitis C virus (HCV) chronic infection can be associated with extrahepatic manifestations
such as mixed cryoglobulinaemia and lymphoproliferative disorders that are endowed with …

Background: To assess the role played by the immune response in the outcome of hepatitis
C virus infection, the CD4+ T-lymphocyte response to viral antigens was studied in infected …

Results Virus elimination was obtained in 26% of patients (responders, R) and a higher
CD8+ level and a decrease in CD4+ was observed during interferon administration in those …

Resolution of hepatitis C virus (HCV) infection requires a complex interplay between innate
and adaptative immune responses. The role of lymphocyte subpopulations during combined …

Objective. Up to now, little was known about the immunological changes of chronic hepatitis
C (CHC) patients treated with direct‐acting antiviral agents (DAAs); we try to explore the …

While hepatitis C virus (HCV)-specific immune responses are attenuated in HCV/HIV co-
infected patients compared to those infected with HCV alone, the reasons for this remain …