Reductions of baseline cerebral blood flow (CBF) of∼ 10–20% are a common symptom of
Alzheimer's disease (AD) that appear early in disease progression and correlate with the …

Background Reduced cerebral blood flow (CBF) contributes to the pathophysiology of
Alzheimer's disease (AD). However, it is unclear whether there is a spatial-temporal-specific …

Therapies targeting late events in Alzheimer's disease (AD), including aggregation of
amyloid beta (Aβ) and hyperphosphorylated tau, have largely failed, probably because they …

There is accumulating evidence suggesting that changes in brain perfusion are present long
before the clinical symptoms of Alzheimer's disease (AD), perhaps even before amyloid-β …

Objective: To investigate variation in the characteristics of regional cerebral blood flow
(rCBF), brain activity, and intrinsic functional connectivity (FC) across the Alzheimer's …

Alzheimer's disease (AD) is a degenerative disorder characterized by a decreased regional
cerebral blood flow (CBF). It is most likely that a reduction in CBF could displace a pathway …

Cerebral blood flow (CBF) reductions in Alzheimer's disease patients and related mouse
models have been recognized for decades, but the underlying mechanisms and resulting …

Cerebral blood flow (CBF) alterations and amyloid-β (Aβ) accumulation have been
independently linked to cognitive deficits in older adults at risk for dementia. Less is known …

Reduced cerebral blood flow (CBF), an indicator of neurovascular processes and metabolic
demands, is a common finding in Alzheimer's disease. However, little is known about what …

Introduction We examined the association between decreased cerebral blood flow (CBF)
and cognitive impairment in Alzheimer's disease (AD), mild cognitive impairment (MCI), and …