Effect of amiodarone on serum triiodothyronine, reverse triiodothyronine, thyroxin, and thyrotropin. A drug influencing peripheral metabolism of thyroid hormones.

A Burger, D Dinichert, P Nicod, M Jenny… - The Journal of …, 1976 - Am Soc Clin Investig
2-n-Butyl-3-(4'-diethylaminoethoxy-3', 5'-diiodobenzoyl)-benzofurane (amiodarone), a drug
used in arrythmias and angina pectoris, contains 75 mg of organic iodine/200 mg active …

Hyperthyroxinemia with bradycardia and normal thyrotropin secretion after chronic amiodarone administration

S MELMED, K NADEMANEE, AW REED… - The Journal of …, 1981 - academic.oup.com
Pituitary-thyroid function was tested in 15 euthyroid patients before, during, and after long
term oral treatment with amiodarone (2-n-butyl-3, 4′-diethylaminoethoxy-3′, 5 …

AMIODARONE AND THYROID HORMONE ACTION JAYNE A.

JA FRANKLYN, JR Davis, MD Gammage… - Clinical …, 1985 - Wiley Online Library
In clinically euthyroid subjects on long‐term amiodarone therapy free thyroxine (T4)
concentrations were increased and free triiodothyronine (T3) levels reduced. There was also …

The effects of amiodarone on serum thyroid hormones and hepatic thyroxine 5′-monodeiodination in rats

PB SOGOL, JM HERSHMAN, AW REED… - …, 1983 - academic.oup.com
Amiodarone (2-n-butyl-3, 4′-diethylaminoethoxy-3′, 5′-diiodobenzoyl-benzofurane) is
an antiarrhythmic drug which increases serum T4 and rT3 levels in patients and lowers …

Are Selective Increases in Serum Thyroxine (T4)due to Iodinated Inhibitors of T4 Monodeiodination Indicative of Hyperthyroidism?

MJ LAMBERT, AG BURGER… - The Journal of …, 1982 - academic.oup.com
The term “T4toxicosis” has been used to describe the selective increase in serum total and
free T4that has been noted in some patients during acute or chronic nonthyroidal illness …

Amiodarone and thyroid hormone metabolism.

WM Wiersinga, MD Trip - Postgraduate Medical Journal, 1986 - ncbi.nlm.nih.gov
Amiodarone, an antiarrhythmic and anti-anginal agent, contains 75mg oforganic iodine per
200mg active substance. The drug is deiodinated during its biotransformation, and it is …

Clinical and chemical assessment of thyroid function during therapy with amiodarone

JA Amico, V Richardson, B Alpert… - Archives of Internal …, 1984 - jamanetwork.com
• Clinical and chemical variables of thyroid function were studied in 26 patients with
symptomatic ventricular tachyarrhythmias before and during long-term oral treatment with …

Effects of amiodarone on thyroid function in patients with ischaemic heart disease.

DA Pritchard, BN Singh, PJ Hurley - Heart, 1975 - heart.bmj.com
Thyroid function was evaluated clinically and biochemically in 12 patients with ischaemic
heart disease receiving 200 mg oral amiodarone three times daily for periods up to 6 weeks …

Effect of long-term amiodarone therapy on thyroid hormone levels and thyroid function

GD Borowski, CD Garofano, LI Rose… - The American journal of …, 1985 - Elsevier
Both hyperthyroidism and hypothyroidism have been noted to occur in some patients treated
with amiodarone for cardiac arrhythmias. To determine the frequency of the development of …

Amiodarone and the thyroid.

RL Kennedy, H Griffiths, TA Gray - Clinical chemistry, 1989 - academic.oup.com
An antiarrhythmic drug, amiodarone, contains 37% iodine by weight and is structurally
similar to the thyroid hormones. The drug inhibits hepatic 5'-deiodinase, resulting in …