Captopril (Capoten) hasbeen evaluated in the treatment both of hypertension and cardiac
failure (Atkinson & Robertson, 1979). However, it is currently indicated only for severe or …

After administration of captopril, a decrease in mean arterial blood pressure was observed in
low sodium rats which were used as animal models of hyper-renin-active athe-ma. In normal …

The purpose of these experiments was to determine the dose of captopril which resulted in
essentially complete blockade of tissue and plasma converting enzyme activity (CEA) and to …

1. Changes in arterial blood pressure, blood angiotensin I, plasma angiotensin II and
plasma angiotensin III were measured in conscious sodium-depleted dogs after infusion of …

Captopril was administered for 6 days to 26 severely hypertensive hospitalized patients, 17
with essential hypertension and 9 with renovascular hypertension. All the patients were on a …

The acute effects of 25 mg captopril on blood pressure, heart rate, components of the renin‐
angiotensin system and blood concentration of bradykinin were followed in a single‐blind …

The orally administered blocker of angiotensin‐converting enzyme, captopril, was given to
16 patients with moderate to severe hypertension in whom blood pressure could not …

The hemodynamic effects of captopril were investigated in 22 patients with essential
hypertension, 22 with hypertension and renal artery stenosis and 14 with refractory chronic …

Twenty severely hypertensive subjects who did not achieve blood pressure control with
combination therapy with a vasodilator, a beta-adrenergic blocking agent and a diuretic …

Eight hypertensive patients on chronic captopril treatment were studied: blood pressure,
plasma converting enzyme activity (pCEA) and various components of plasma renin …