Captopril (SQ 14225) or hydrochlorothiazide was given to a group of 20 patients with
essential hypertension for four weeks, followed by eight weeks' therapy with both drugs …

To determine if food reduces the hemodynamic and humoral effects of captopril in patients
with essential hypertension, we performed two studies. In the acute study, 15 inpatients with …

The ability of captopril (SQ-14225), an angiotensin I-converting enzyme inhibitor, to reduce
blood pressure in dogs anesthetized with either pentobarbital sodium or a combination of …

The orally active angiotensin converting enzyme inhibitor, captopril, was administered to 23
hypertensive patients maintained for 10 days on a constant sodium and potassium intake …

The effects of Captopril on blood pressure and renal function were evaluated in ten patients
with different degrees of hypertension. In seven, blood pressure was reduced after 7 weeks …

Nine patients with essential hypertension treated with bendroflumethiazide were given
captopril 25 mg orally on three occasions to study the pharmacokinetics and blood pressure …

Eight hypertensive patients with normal renal function and receiving diuretic therapy for at
least 28 days received captopril in small increasing doses (6.25, 12.5, and 25 mg). Supine …

The angiotensin-converting enzyme inhibitor, captopril, was given to 19 patients with severe
heart failure. Seven patients had acute myocardial infarction and the remainder had chronic …

• The effect of low doses (25 mg three times a day) of captopril was evaluated in 16 patients
with mild to moderate essential hypertension, previously uncontrolled by …

We studied the effect of a converting enzyme inhibitor (CEI), Captopril SQ 14,225 50 mg po
in eight supine normal subjects under a high sodium (150 meq/d) and low sodium (25 …