Opinion statement With advances in treatments and survival of patients with glioblastoma
(GBM), it has become apparent that conventional imaging sequences have significant …

MRI is routinely used for diagnosis, treatment planning and assessment of response to
therapy for patients with glioma. Gliomas are spatially heterogeneous and infiltrative lesions …

Objective Summarize evidence for use of advanced MRI techniques as monitoring
biomarkers in the clinic, and highlight the latest bench-to-bedside developments. Methods …

Aside from bidimensional measurements from conventional contrast-enhanced MRI, there
are no validated or FDA-qualified imaging biomarkers for high-grade gliomas. However …

Purpose To integrate standard anatomic magnetic resonance imaging in conjunction with
uniformly acquired physiologic imaging biomarkers of untreated glioma with different …

Pseudophenomena, that is, imaging alterations due to therapy rather than tumor evolution,
have an important impact on the management of glioma patients and the results of clinical …

Magnetic resonance (MR) imaging provides excellent soft tissue differentiation and in vivo
assessment of physiologic and metabolic properties of tissue. As new and more aggressive …

There exist multiple challenges associated with the current response assessment criteria for
high-grade gliomas, including the uncertain role of changes in nonenhancing T2 …

The wide variety of treatment options that exist for glioblastoma, including surgery, ionizing
radiation, anti-neoplastic chemotherapies, anti-angiogenic therapies, and active or passive …

Glioblastoma, the most common malignant primary brain tumor in adults is a devastating
diagnosis with an average survival of 14–16 months using the current standard of care …