Carbazole based novel multifunctional agents has been rationally designed and
synthesized as potential anti-Alzheimer agents. Multi-functional activity of these derivatives …

Multi-Target approach is particularly promising way to drug discovery against Alzheimer's
disease. In the present study, we synthesized a series of compounds comprising the …

Introduction Alzheimer's disease (AD) is one of the most common and prevalent forms of
neurodegenerative diseases. Coumarin is a versatile scaffold that exhibits a wide range of …

Alzheimer's disease (AD) is a major public health problem. The dual inhibitors of
monoamine oxidase-B (MAO-B) and acetyl cholinesterase (AchE) are reported as effective …

A series of multi-target natural product-pyridoxine based derivatives were designed,
synthesized, characterized and evaluated as anti-Alzheimer agents. In vitro testing revealed …

Abstract Development of Multi-Target Directed Ligands (MTDLs) has emerged as a
promising approach for targeting complex etiology of Alzheimer's disease (AD). Following …

To discover multifunctional agents for the treatment of Alzheimer's disease (AD), a series of
chalcone-O-carbamate derivatives was designed and synthesized based on the multitarget …

Alzheimer's is a neurodegenerative disease (NDs) found in old age people with associated
most common symptom dementia. MTDLs (Multi-Target Direct Ligand strategy) is based on …

Alzheimer's disease (AD) is a progressive neurological illness that is distinguished clinically
by cognitive and memory decline and adversely affects the people of old age. The …

New compounds containing thiazole and pyridinium moieties were designed and
synthesized. The potency of the synthesized compounds as selective inhibitors of …